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ISSN 1561-2996 (Electronic)
ISSN 0864-0289 (Print)

2014, Number 2

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Rev Cubana Hematol Inmunol Hemoter 2014; 30 (2)

Prevalence of hemophilia in six cuban provinces

Castillo GD, Lardoeyt FR, Almagro VD, Lam DRM, Lavaut SK, Gutiérrez DA, Campo DM, Álvarez VN, Salinas GJL, Fernández ÁJD, Agramonte-Llanes O

Language: English
References: 8
Page: 155-161
PDF size: 90.96 Kb.


ABSTRACT

Introduction: hemophilia is an inherited bleeding disorder; its incidence is almost constant in different populations. Since the 80th decade a multidisciplinary group for the care of patients with hemophilia was created at the Instituto de Hematología e Inmunología. Nowadays a national comprehensive care program allows patients to receive a continuous monitoring and an effective treatment.
Objective: to know prevalence of patients with hemophilia in Cuba.
Results: data of 229 patients from 5 provinces and the special municipality Isla de la Juventud were included, which covered 58,71% of the total patients registered in Cuba. The information included demographic data, severity of hemophilia, presence of inhibitors and infection status for viral diseases. Hemophilia A patients were 188 (82.10%) and 41 (17.90%) with hemophilia B. The disease was severe in 56.33 % of patients, moderate in 24 %, and mild in 19.70 %. Inhibitors were present in 17.03 % of the patients. Human immunodeficiency virus infection was present only in 0.87 % of patients and hepatitis C virus infection in 39.03 %. The mean age at diagnosis was 2.15 years.
Conclusions: the general age-adjusted prevalence was 9.63 cases of hemophilia per 100 000 male and the main prevalence of patients was found in ages between 20 and 59 years.


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