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2012, Number S1

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Mul Med 2012; 16 (S1)

Evaluation of the antimicrobial activity of the extracts of Mirabilis jalapa L.

Castillo MA, Pascual SYM, de los Ángeles CF, de la Paz LC
Full text How to cite this article

Language: Spanish
References: 6
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Key words:

mirabilis, phytotherapy.

ABSTRACT

With the aim of evaluating the antimicrobial activity in vitro of natural extracts of the leaves and stems of wonder (Mirabilis jalapa l.), it was performed a research in the Center of Study of Applied Chemistry of the University of Granma and in the Microbiology Laboratory at Celia Sánchez Manduley Hospital. For that purpose it was applied a phytochemical screening using simple techniques in order to identify the main metabolites with possible antimicrobial effect. The antimicrobial activity of the products obtained was assessed using the Kirby-Bauer method. The dry, clorophormic, hexanic and ethyl acetate extracts presented activity to 20%. It was also determined by chromatography of thin skin that the extracts contained: quinones, coumarins and flavonoids. These results permitted to check the variability of chemical compounds, which justifies its use in a traditional way by the population.


REFERENCES

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  2. Murray PR, Baron EJ, Faller MA, Tenover FC, Yolken RH. Manual of Clinical Microbiology, 7th ed. Washington, DC: ASM; 1999.

  3. Rossi C, Arias G, Lázaro N. Evaluación antimicrobiana y fitoquímica de Lepechenia meyeni. Walp. Salvia. Ciencia e Investigación 2002; 5(1).

  4. Ponce A, Roura S, Del Valle C, Moreira M. Antimicrobial and antioxidant activities of edible coantings enriched with natural plant extracts: in vitro and in vivo studies. Postharvest Biology and Technology 2008; 49: 294-300.

  5. Tavarez W. Bacterias gram positivas problemas: resistencia do estafilococo, do enterococo e do pneumococo aos antimicrobianos. Rev da Sociedade Brasileira de Med Trop 2000; 33(3).

  6. Wallace RJ. Antimicrobial properties of plant secondary metabolites. Proc Nutr Soc 2004; 63 (4): 621-9.




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Mul Med. 2012;16