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ISSN 1561-3070 (Electronic)

2014, Number 1

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Rev Cub Oftal 2014; 27 (1)

50 % autologous serum in bacterial keratitis

Cambas AAA, Parapar TSI, González RO, Guerra AM, de Prada SC, Lora DK

Language: Spanish
References: 17
Page: 70-78
PDF size: 338.61 Kb.


ABSTRACT

Objective: to evaluate the behavior of bacterial keratitis with the adjuvant 50% topical autologous serum treatment.
Methods: comparative, longitudinal and prospective study of 60 patients, randomly distributed into two groups. Group A used the conventional antibiotics treatment plus autologous serum and Group B used only conventional antibiotics treatment (cephazolin and amykacin). The collected data were processed by the statistical package SPSS15. The variables were expressed according to their respective summary measures and hypothesis tests were applied to compare the two therapies; a confidence level of 95 % and error level less than 0,05 % were used.
Results: in the microbiological isolates, Staphylococcus and Pseudomonas prevailed, followed by Streptococcus, gonococci and Enterobacteriaceae. Regarding the time of onset of the signs that favor corneal healing and the therapeutic response, it was found that with the topical application of the autologous serum, almost two thirds of the patients showed healing signs since the second week of treatment, revealing a favorable therapeutic response.
Conclusions: the 50 % autologous serum proves to be an effective therapeutic complement in the management of the infectious keratitis of bacterial etiology.


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