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Colegio de Medicos y Cirujanos República de Costa Rica
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2014, Number 610

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Rev Med Cos Cen 2014; 71 (610)

Enfermedad Peyronie

Stanford VL, Esquivel VLF
Full text How to cite this article

Language: Spanish
References: 11
Page: 327-332
PDF size: 286.11 Kb.


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ABSTRACT

The first description of Peyronie’s disease is given to Francois Gigot de la Peyronie in 1743. It is a pathology characterized by an acquired inflammatory disorder, abnormal scarring with deposition of collagen and fibrin forming a fibrous plaque and a reduction in elastic fibers in the tunica albuginea of the penis. This entity is characterized by pain with erection, curvature and deformity accompanied in some cases by erectil dysfunction. With an incidence rate of approximately 3.2% to 8.9%, the average age at onset of this disease is seen in the fourth to sixth decade of life. Treating the disease will depend on the stage in which it is found at the time of diagnosis. There are oral, intralesional and surgical treatments discussed with detail in this review.


REFERENCES

  1. Berookhim BM, Choi J, Alex B, Mulhall JP. Deformity Stabilization and Improvement in Men with Untreated Peyronie’s Disease. BJU Int. 2013 Jul 2; Pp. 1-12

  2. Gelbard M, Goldstein I, Hellstrom WJ, McMahon CG, Smith T, Tursi J, Jones N, Kaufman GJ, Carson CC 3rd Clinical efficacy, safety and tolerabililty of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studied. Journal Urology 2013 Jul; Pp. 199- 207

  3. Halal AA, Geavlete P, Ceban E. Pharmacological therapy in patients diagnosed with Peyronie’s disease. Journal of Medicine and Life. 2012 Jun; Pp. 192-195

  4. Hatzichristodoulou G, Meisner C, Gschwend JE, Stenzl A, Lahme S. Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Results of a Placebo-Controlled, Prospective, Randomized, Single- Blind Study. Journal Sex Med. 2013 Jul 30; Pp. 1-7

  5. Hyuk Jang J, Kan Ryu Ji, Kyu Suh J. Activin Receptor-Like Kinase 5 Inhibitor Atteuates Fibrosis in Fibroblasts Derived from Peyronie’s Plaque. Korean Journal of Urology. 2012; Pp. 44-49

  6. Kalokairinou K, Konstantinidis C, Domazou M, Kalogeropoulos T, Kosmidis P, Gekas A. US Imaging in Peyronie’s Disease. J Clinic Imaging Sci. 2012 Oct 31; Pp. 1-11

  7. Langston JP, Carson CC 3rd. Peyronie Disease: plication or grafting. Urology Clinics of North America. 2011 Feb 24; Pp. 207-216

  8. Schaeffer AJ, Burnett AL. Nonsurgical interventions for Peyronie disease: 2011 update. Journal of Andrology 2012 Jan; Pp. 3-14

  9. Trost LW, Ates E, Powers M, Sikka S, Hellstrom WJ. Outcomes of Intralesional Interferon-alfa2B for the Treatment of Peyronie’s Disease. Journal Urology 2013 May 18; Pp. 1-6

  10. Wein AJ et al, Cambpell-Walsh. Urology. Sauders Elsevier, vol 1-3, 10 edición, 2012; Pp. 64-66, 792- 809

  11. Wieder Jeff A. Pocket Guide to Urology. Griffith, 4 edición, 2010; Pp. 342-345




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Rev Med Cos Cen. 2014;71