Rodríguez RM

Language: Spanish
References: 13
Page: 13-15
PDF size: 310.35 Kb.

ABSTRACT

Alfphafetoprotein increase has been related to fetal defects and other pregnancy complications such as low weight and preterm birth. The goal of this study was to verify the relationship between high AFP-UMELISA and low weight at birth and preterm birth. A prospective analysis was carried out from January 2008 to December 2008. A group of pregnant women whose alphafetoprotein content was higher than or equal to 2.0 MoM without apparent cause were selected as well as a control group having a normal content of this protein in maternal serum. The pregnant women with high alphafetoprotein content were found to have a relative risk of 2.82 for low weight at birth in relation to the pregnant women with a normal content (IC 1.91-4.17) and 2.05 for preterm birth (IC 1.43-2.94). When alphafetoprotein contents higher than 2.3 MoM were analyzed, the risk of low weight at birth increased to 2.64 (IC: 2.31-5.75) and decreased to 1.95 (IC 1.20-3.17) for preterm birth. The study showed the association of high contents of the AFPUMELISA test and low weight at birth and preterm birth. Using the 2.3 MoM cut value increased the risk relating to low weight at birth.

REFERENCES

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