medigraphic.com
SPANISH

Revista del Hospital Juárez de México

  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2014, Number 2

<< Back Next >>

Rev Hosp Jua Mex 2014; 81 (2)

Comparison of modeling techniques used to characterize moderate and heavy phase two recovery Vo2 kinetics in old men

Padilla-Pérez J
Full text How to cite this article

Language: Spanish
References: 34
Page: 92-103
PDF size: 272.69 Kb.


Key words:

Old men, post-exercise recovery, off-O2 uptake kinetics, phase two O2, exponential modelling, time constant.

ABSTRACT

We kinetically assessed pulmonary oxygen uptake (VO2) off-transient (Post-Exercise Recovery) response during moderate (M)- and heavy (H)-intensity (Sub = M + H) exercise comparing among several common modelling strategies to assess the best fitting exponential model. The parameter estimated for phase 2 VO2 was the time constant (off-τΦ2VO2) in older male adults [n = 9; 72 (±4) yrs; mean (±sd)]. Subjects performed an incremental ramp test (12 W•min-1) to the limit of tolerance to determine VO2peak and the estimated lactate threshold (VET). Constant-load cycle exercise was performed at 50 W (M) and work rates corresponding to 80% (M) and 120% VET (H). Each transition in work rate lasted 6 min and was preceded by 6 min cycling at a baseline of 20 W; transitions at each intensity were repeated 4-6 times. VO2 was measured breath-by-breath. Each subject pedalled at 60 rpm and protocol began with a base line off 1 min end exercise load-cycling, followed by a step decrease in power output (without warning the subject) back to loadless cycling lasting 6 min in duration (PER). Data from each transition were filtered, interpolated to 1 s intervals and ensemble-averaged to yield a single response profile for each subject and intensity. Responses were modelled by means of nonlinear regression techniques with one-(1C), two-(2C) and three-component (time delay) (3C) exponential models using different fitting windows. The off-Φ2VO2 for Sub was both physiologically and stastistically well described and kinetically characterized (off-τ2VO2) by a two component doble exponential function (2C) for M (aτ2 = 56 ± 14 s)-, and by a threecomponent triple exponential function (3C) (bτ2 = 39 ± 7, agbP ‹ 0.05) for H in old men.


REFERENCES

  1. Poole DC, Jones AM. Oxygen Uptake Kinetics. Compr Physiol 2012; 2(2): 933-96.

  2. Cunningham DA, Croix CM, Paterson DH, Ozyener F, Whipp BJ. The off-transient pulmonary oxygen uptake (O2) kinetics following attainment of a particular O2 during heavy-intensity exercise in humans. Exp Physiol 2000; 85(3): 339-47.

  3. Chilibeck PD, Paterson DH, McCreary CR, Marsh GD, Cunningham DA, Thompson RT. The effects of age on kinetics of oxygen uptake and phosphocreatine in humans during exercise. Exp Physiol 1998; 83(1): 107-17.

  4. Behnke BJ, Ferreira LF, McDonough PJ, Musch TI, Poole DC. Recovery dynamics of skeletal muscle oxygen uptake during the exercise off-transient. Respir Physiol Neurobiol 2009; 168(3): 254-60.

  5. Whipp BJ. The bioenergetics and gas exchange basis of exercise testing. Clin Chest Med 1994; 15: 173-92.

  6. Simões RP, Bonjorno JC Jr, Beltrame T, Catai AM, Arena R, Borghi-Silva A. Slower heart rate and oxygen consumption kinetic responses in the on- and off-transient during a discontinuous incremental exercise: effects of aging. Braz J Phys Ther 2013; 17(1): 69-76.

  7. Gerbino A, Ward SA, Whipp B J. Effects of prior exercise on pulmonary gas-exchange kinetics during high-intensity exercise in humans. J Appl Physiol 1996; 80: 99-107.

  8. Paterson DH, Whipp BJ. Asymmetries of oxygen uptake transients at the on- and offset of heavy exercise in humans. J Physiol 1991; 443: 575-86.

  9. Bangsbo YJ, Gollnick PD, Graham TE, Juel C, Kiens B, Mizuno M, Saltin B. Anaerobic energy production and 02 deficit-debt relationship during exhaustive exercise in humans. J Physiol 1990; 422: 539-59.

  10. Gore CJ, Withers RI. Effects of exercise intensity and duration on postexercise metabolism. J Appl Physiol 1990; 68: 2362-8.

  11. Short KR, Sedlock DA. Excess postexercise oxygen consumption and recovery rate in trained and untrained subjects. J Appl Physiol 1997; 83(1): 153-9.

  12. Margaria R, Edwards HT, Dill DB. The possible mechanisms of contracting and paying the oxygen debt and the role of lactic acid in muscular contraction. Amer J Physiol 1933; 106: 689-715.

  13. Davies CTM, Diprampero PE, Cerretelli P. Kinetics of cardiac output and respiratory gas exchange during exercise and recovery. J Appl Physiol 1972; 32: 618-25.

  14. Whipp BJ, Ward SA, Rossiter HB. Pulmonary O2 uptake during exercise: conflating muscular and cardiovascular responses. Med Sci Sports Exerc 2005; 37: 1574-85.

  15. Linnarsson, D. Dynamics of pulmonary gas exchange and heart rate changes at the start and end of exercise. Acta Physiol Scand 1974; suppl. 414: 1-68.

  16. Hill AV, Lupton H. Muscular exercise, lactic acid and the supply and utilization of oxygen. Q J Med 1923; 16: 135-71.

  17. Özyener F, Rossiter HB, Ward SA, Whipp BJ. Influence of exercise intensity on the on- and offtransient kinetics of pulmonary oxygen uptake in humans. J Physiol 2001; 533;3: 891-902.

  18. Fukuoka Y, Grassi B, Conti M, Guiducci D, Sutti M, Marconi C, Cerretelli P. Early effects of exercise training on on- and offkinetics in 50-year-old subjects. Pflugers Arch 2002; 443(5-6): 690-7.

  19. Wasserman K, Hansen JE, Sue DY, Whipp BJ. Principles of exercise testing and interpretation. Philadelphia: Lea Febiger; 1987.

  20. Paterson DH, Cunningham DA, Babcock MA. Oxygen kinetics in the elderly. Respiratory Control: A Modelling Perspective. In: Swanson GD, Grodins FS, Hughson RL (eds.). New York: Plenum Press; 1989, p. 171-8.

  21. Padilla JP, Kowalchuk JM, Taylor AW, Paterson DH. Comparison of model estimates of phase two on-transient O2 uptake kinetics during submaximal exercise in old men. Rev Hosp Jua Mex 2008; 75(3): 151-65.

  22. Beaver WL, Lamarra N, Wasserman K. Breath-by-breath measurements of true alveolar gas exchange. J Appl Physiol 1981; 51: 1662-75.

  23. Padilla JP. Slow age-related phase ii on-transient O2 kinetics heart rate kinetics during ramp exercise in adult men. Rev Hosp Jua Mex 2010; 77(4): 245-54.

  24. Bell C, Paterson DH, Kowalchuk JM, Padilla J, Cunningham DA. A comparition of modelling techniques used to characterize oxygen uptake kinetics during the on-transient of exercise ”muscle”. Exp Physiol 2001; 86(5): 667-76.

  25. Motulsky HJ, Ransnas A. Fitting curves to data using nonlinear regression: a practical and nonmathematical review. FASEB J 1987; 1: 365-74.

  26. Zar JH. Biostatistical Analysis. 3rd Ed. New Jersey: Prentice Hall, Inc., U.S.A.; 1996.

  27. Marquardt DW. An algorithm for least-squares estimation of nonlinear parameters. J Soc Induct Appl Math 1963; 11(2): 431-41.

  28. Gaesser GA, Brooks GA. Metabolic basis of excess postexercise oxygen consumption: a review. Med Sci Sports Exerc 1984; 16(1): 29-43.

  29. Padilla JP. Comparison of modelling techniques used to characterize moderate and heavy phase two recovery O2 kinetics in young men. Rev Hosp Jua Mex 2012; 79(3): 159-73.

  30. Casaburi R, Storer TW, Ben Dov I, Wasserman K Effect of endurance training on possible determinants of O2 during heavy exercise. J Appl Physiol 1987;62:199-207.

  31. Brittain CJ, Rossiter HB, Kowalchuk JM, Whipp BJ. Effect of prior metabolic rate on the kinetics of oxygen uptake during moderate-intensity exercise. Eur J Appl Physiol 2001; 86: 125-34.

  32. Barstow TJ, Molé PA. Linear and nonlinear characteristics of oxygen uptake during heavy exercise. J Appl Physiol 1991; 71: 2099-106.

  33. Tschakovsky ME, Hughson RL. Interaction of factors determining oxygen uptake at the onset of exercise. J Appl Physiol 1999; 86: 1101-13.

  34. Perrey S, Candau R, Borrani F, Millet GY, Rouillon JD. Recovery kinetics of oxygen uptake following severe-intensity exercise in runners. J Sports Med Phys Fitness 2002; 42(4): 381-8.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Hosp Jua Mex. 2014;81