medigraphic.com
ISSN 2007-6800 (Print)

2014, Number 2

<< Back Next >>

Rev Mex Traspl 2014; 3 (2)

Evaluation of quality of life in patients with liver transplant

Mendoza-Sánchez F, Ramírez-González LR, Reyes-Cruz AA, González-Ojeda A, Chávez-Tostado MG, Macías-Amezcua MD, Hernández-Machuca JS, Cervantes-Pérez E, García-Ramírez BE, Fuentes-Orozco C

Language: Spanish
References: 16
Page: 44-48
PDF size: 228.53 Kb.


ABSTRACT

Background: Less than ten percent of patients undergoing liver transplantation may develop complications. Short-term and/or long-term complications can include vascular, biliary, graft rejection and side effects of immunosuppressive drugs. Objective: The goal of this study is to assess quality of life after cadaveric donor liver transplantation. Material andmethods: This is a case series study. Quality of life after cadaveric donor liver transplantation between January 1st, 2005 and December 31st, 2012 was evaluated. Variables like age, gender, time after transplantation, etiology of liver cirrhosis and immunosuppressive drugs were analyzed. We used the short-form 36 (SF-36) version 1.1 quality of life questionnaire, previously validated in Mexican patients. Results: Thirty seven patients admitted to hospital were included in the study. There were 25 (67.6%) females and 12 (32.4%) males. Mean age, 48.7 years (range 20-69). The most common cause was cirrhosis of the liver, n = 35 (94.5%). The highest score in the top quartile was seen in mental health (56.7%), social role functioning (54%) and emotional role functioning (54%). The highest score in the lowest quartile was seen in physical role functioning (10.8%). The mean time after liver transplantation was 6.73 ± 3.53 years. Conclusions: Liver transplantation can increase life expectancy and improve the quality of life. The SF-36 results were similar to other health surveys.


REFERENCES

  1. Santoyo J, Suárez MA, Fernández Aguilar JL et al. Resultados actuales del trasplante hepático split: morbilidad, mortalidad y supervivencia. Cir Esp. 2004; 76 (S3): 3-8.

  2. Kim WR, Stock PG, Smith JM, Heimbach JK, Skeans MA, Edwards EB et al. OPTN/SRTR 2011 Annual Data Report: liver. Am J Transplant. 2013; 1: 73-102.

  3. Kousoulas L, Neipp M, Barg-Hock H, Jackobs S, Strassburg CP, Klempnauer J et al. Health-related quality of life in adult transplant recipients more than 15 years after orthotopic liver transplantation. Transpl Int. 2008; 21 (11): 1052-1058.

  4. Guyatt GH, Cook DJ. Health status, quality of life, and the individual. JAMA. 1994; 272 (8): 630-631.

  5. Cohen SR, Mount BM, MacDonald N. Defining quality of life. Eur J Cancer. 1996; 32A (5): 753-754.

  6. Szabo E1, Moody H, Hamilton T, Ang C, Kovithavongs C, Kjellstrand C. Choice of treatment improves quality of life. A study on patients undergoing dialysis. Arch Intern Med. 1997; 157 (12): 1352-1356.

  7. Zúniga MA, Carrillo-Jiménez GT, Fos PJ, Gandek B, Medina-Moreno MR. Evaluation of health status using Survey SF-36: preliminary results in Mexico. Salud Pública Mex. 1999; 41 (2): 110-118.

  8. Gotardo DR, Strauss E, Teixeira MC, Machado MC. Liver transplantation and quality of life: relevance of a specific liver disease questionnaire. Liver Int. 2008; 28: 99-106.

  9. Durán-Arenas L, Gallegos-Carrillo K, Salinas-Escudero G, Martínez-Salgado H. Hacia una base normativa mexicana en la medición de calidad de vida relacionada con la salud, mediante el Formato Corto 36. Salud Pública de Méx. 2004; 46 (4): 306-315.

  10. Metselaar HJ, Tilanus HW, Stam HJ. Physical fitness, fatigue, and quality of life after liver transplantation. Fatigue after Liver Transplantation. 2009; 100: 55.

  11. Van Ginneken BTJ, van den Berg-Emons RJG, Kazemier G, Metselaar HJ, Tilanus HW, Stam HJ. Physical fitness, fatigue, and quality of life after liver transplantation. Eur J Appl Physiol. 2007; 100: 345-353.

  12. Saab S, Wiese C, Ibrahim AB, Peralta L, Durazo F. Employment and quality of life in liver transplant recipients. Liver Transpl. 2007; 13: 1330-1338.

  13. McHorney CA, Ware JE Jr. Lu JF, Sherbourne CD. The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups.

  14. Arenas AC, Galindo M, Diliz H, Rodríguez Weber F. Calidad de vida en pacientes del Hospital Ángeles del Pedregal con trasplante hepático. Med Int de Mex. 2011; 27 (2): 113-119.

  15. Chen PX, Yan LN, Wang WT. Health-related quality of life of 256 recipients after liver transplantation, World J Gastroenterol. 2012; 18 (36): 5114-5121.

  16. Duffy JP, Kao K, Ko CY, Farmer DG, McDiarmid SV. Long-term patient outcome and quality of life after liver transplantation: analysis of 20-year survivors. Ann Surg. 2010; 252 (4): 652-661.




2020     |     www.medigraphic.com