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ISSN 1561-3011 (Electronic)

2014, Number 1

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Rev Cubana Invest Bioméd 2014; 33 (1)

Determination of bioactivity in sodium alginate layers of hydroxyapatite disks

Fernández AME, Alves JC, González RJE, Valin FM, Valin RJL

Language: Spanish
References: 19
Page: 34-43
PDF size: 609.60 Kb.


ABSTRACT

Objective: the main purpose of the study is to evaluate in vitro bioactivity in sodium alginate layers of hydroxyapatite disks.
Methods: the hydroxyapatite disks were manufactured by successive pressing and sintering in an electric furnace. The sodium alginate layers were obtained by overpressure and a 5% sodium alginate aqueous solution. For the bioactivity assay, the study samples were soaked in simulated biological fluid. Characterization of the samples was conducted by scanning electron microscopy and energy dispersive X rays.
Results: the bioactivity assay of hydroxyapatite samples with and without sodium alginate layers revealed the formation of precipitates rich in calcium and phosphorus. It was also found that an increase in the time of immersion in the simulated biological fluid brought about an increase in the size of agglomerates of apatite particles.
Conclusions: experimental results show that hydroxyapatite is indeed bioactive, and that the sodium alginate layers of hydroxyapatite disks which were studied behave bioactively.


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