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Revista Mexicana de Ortopedia Pediátrica

ISSN 2007-087X (Print)
Órgano Oficial de la Sociedad Mexicana de Ortopedia Pediátrica
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2014, Number 1

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Rev Mex Ortop Ped 2014; 16 (1)

Preliminary results on the development of a mathematical model to predict the water content of cartilage by magnetic resonance

Shiguetomi MJM, Ramírez García-Luna JL, Gottliebsen M, Kristiansen MS, Ringgaard S, Stødkilde-Jørgensenh H, Rahbek O, Møller-Madsen B
Full text How to cite this article

Language: Spanish
References: 5
Page: 26-28
PDF size: 133.96 Kb.


Key words:

Cartilage, magnetic resonance, T11.

ABSTRACT

Introduction: Cartilage is a tissue composed by approximately 80% water. Through magnetic resonance strings it is possible to correlate the tissue’s signal intensity with water content; therefore, the objective of this study was to develop a mathematical model to estimate water content in percentage in a cartilage sample. Material and methods: Through absolute T1 value mapping and inverse recovery sequence magnetic resonance strings 45 agar blocks with progressive and known water concentrations (70-100%) were analyzed. Data obtained was modelled in a lineal regression to obtain a water content prediction equation. Results: The equation water content ~ T1 signal intensity correlates with a r2 = 0.9715 (p ‹ 0.001) with the real water content in the agar blocks. Discussion: T1 magnetic resonance strings provide enough information on the quantity of water present in a tissue with a predictive value near 98%


REFERENCES

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  2. Winalski CS, Rajiah P. The evolution of articular cartilage imaging and its impact on clinical practice. Skeletal Radiol. 2011; 40(9): 1197-1222.

  3. Xie L, Lin ASP, Kundu K, Levenston ME, Murthy N, Guldberg RE. Quantitative imaging of cartilage and bone morphology, reactive oxyten species, and vascularization in a rodent model of osteoarthritis. Arthritis Rheum Forthcoming. 2013. doi: 10.1002/art.34370

  4. Cutillo AG, Morris AH, Ailion DC, Durney CH, Ganesan K. Determination of lung water content and distribution by nuclear magnetic resonance. In: Rügheimer E (editor). New Aspects on Respiratory Failure. Berlin Heidelberg: Springer-Verlag; 1992. doi: 10.1007/978-3-642-74943-8_15

  5. Shiguetomi-Medina JM, Gottliebsen M, Kristiansen MS, Ringgaard S, Stødkilde-Jørgensen H, Rahbek O et al. Water-content calculation in growth plate and cartilage using MR T1-mapping design and validation of a new method in a porcine model. Skeletal Radiol. 2013; [Epub ahead of print]




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Rev Mex Ortop Ped. 2014;16