Espejo FR, Albrandt SA, Hernández OJ, Funes TEW, Guerrero HM

Language: Spanish
References: 7
Page: 205-208
PDF size: 761.82 Kb.

ABSTRACT

Cistoadenoma Phyllodes (CAP) is a rare, predominantly benign tumor, occurring almost exclusively in feminine mammary glands. In general, the tumor shows the features of a large, malign sarcoma with the appearance of a leave when dissected, and is laid out in the pseudocystic epithelial spaces. Due to the fact that most tumors are benign, the name is confusing; thus, the current terminology being suggested is Phyllodes tumor. Its etiology is still unknown. Usually, a solid, mobile, will defined painless mass is felt. Curiously, the CAP tends to be more frequent in the left mammary gland. While mammographies and ultrasound are important in diagnosing the mammary lesions in general, they are not useful in differentiating diagnosis amongst fibroadenomas, benign CAP and malign CAP, reason for which the final diagnosis cannot be performed by image studies. Incision biopsy is the final method to be able to diagnose the lesion. Its microscopic features are very similar to those of a fibroadenoma, but they show greater cell growth cycle (cellularity) and pleomorphism of stoma components. It shows some tissue projections into cystic cavities. In most cases, the treatment is surgery involving broad excision of the tumor. Response to chemotherapy and radiotherapy in the cases of recurrent and metastasis has been poor. Hormone manipulation therapy has not been well documented. Limited tumor invasion is frequently observed. Recurrent rate in tumors that do not undergo radical mastectomy varies between 15 and 20%.

REFERENCES

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