Mosquera BG, Puentes ÁA, Hernández GEH, Larquin CJI, Chaparro MW

Language: Spanish
References: 14
Page: 156-160
PDF size: 422.44 Kb.

ABSTRACT

Introduction: The inherent complexity of diseases demands a multidisciplinary attention to assure better results for patients. Intraspinal neoplasms are an example of this affirmation and however they don’t have the highest frequency, the clinical and radiological characteristics could become in a challenge for medical staff. Objective: to present a patient with an uncommon lumbar intraspinal neoplasm.
Clinical case: A 31 year old white male patient with an onset of back and sciatic pain and left leg paresthesias and signs of radicular entrapment of the fourth and fifth lumbar roots. Lumbar spine radiological study by computerized tomography and magnetic resonance imaging showed the presence of a neoplasm who invaded the spinal canal and infiltrated the third lumbar vertebral body. Surgical treatment was decided by a staff of orthopedics and neurosurgeons. A laminectomy of the second to forth lumbar vertebrae was made, total complete removal of the neoplastic lesion, curettage of the affected vertebral body, followed by vertebral fusion with spinous apophysis and Luque technique. The trans-operatory pathological diagnosis was Hodgkin lymphoma. The post-operatory follow up included hematology management with specific chemotherapy. The patient has a favorable evolution with two years of asymptomatic survival and without handicap.
Conclusions: The precocious diagnosis of spine neoplasm toward an opportune and suitable treatment by a multidisciplinary team, assures the best results with a favorable repercussion in patients prognosis.

REFERENCES

1. Grimm S, Chamberlain M. Hodgkin's Lymphoma: A Review of Neurologic Complications. Adv Hematol. [serie en internet] 2011 [citado 15 Jul 2013];2011 [aprox. 7 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957132.

2. Kasper EM, Lam FC, Luedi MM, Zinn PO, Pihan GA. Primary epidural lymphocyte-depleted Hodgkin’s lymphoma of the thoracic spine – presentation of a rare disease variant. BMC Neurol. [serie en internet] 2012 [citado 15 Jul 2013];12(64): [aprox. 5 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482592/.

3. Bender RA, Liu AY, Sohani AR, Vyas JM. Hodgkin's lymphoma masquerading as vertebral osteomyelitis in a man with diabetes: a case report. Med Case Reports.

4. G. Mosquera Betancourt et al

5. Rev Cubana Neurol Neurocir. 160 2014;4(2):156–60

6. [serie en internet]2010 [citado 15 Jul 2013];4(102): [aprox. 6 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907869/?report=classic

7. Iacoangeli M, Di Rienzo A, Nocchi N, Alvaro L, Colasanti R, Herber N, et al. An Unusual Instrumentation-Related S1 Radiculopathy in a Patient Treated for a Primary Vertebral (L3) Lymphoma. Clin Med Insights Oncol. [serie en internet] 2012 [citado 15 Jul 2013]; 6: [aprox. 5 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/23226078

8. Breibach F, Julian A, Laurent C, Anglade E, Costantin A, Sans N, et al. Contribution of the 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography to the diagnosis of primary osseous Hodgkin lymphoma. BMJ Case Rep.[serie en internet] 2009 [citado 15 Jul 2013]; 2009: [aprox. 4 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029632/

9. Banerjee D. Recent Advances in the Pathobiology of Hodgkin’s Lymphoma: Potential Impact on Diagnostic,

10. Predictive, and Therapeutic Strategie. Advances in Hematology. [serie en internet] 2011[citado 15 Jul 2013]; 2011: [aprox. 19 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034907

11. Hackembruch HJ, Perna A, Hayek G, Verdier V, Devita A, Benelli L. Compresión medular por Linfoma primitivo extradural en paciente con SIDA: A propósito de un caso. Arch Med Int. 2008; XXX(2-3):76-8.

12. Malli R, Sharma M, Velho V. Primary Lumbo-sacral Spinal Epidural Non-Hodgkin's Lymphoma: A Case Report and Review of Literature. Asian Spine J. 2011;5(3):192–5.

13. Zha Y, Li M, Yang J. Dynamic Contrast Enhanced Magnetic Resonance Imaging of Diffuse Spinal Bone Marrow Infiltration in Patients with Hematological Malignancies. Korean J Radiol. 2010;11(2):187-94.

14. Tang Y, Yang X, Xiao J, Liu K, Yan W, Song D, et al. Clinical outcomes of treatment for spinal cord compression due to primary non-Hodgkin lymphoma. Spine J. 2013;13(6):641-50.