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ISSN 1684-1824 (Electronic)

2014, Number 5

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Rev Méd Electrón 2014; 36 (5)

Thyroids papillary carcinoma, diffuse sclerosal variant, one of its many facets

Castro MAM, Castañeda MAM, González RD, Ríos SM, Madruga VK

Language: Spanish
References: 12
Page: 631-636
PDF size: 442.94 Kb.


ABSTRACT

Background: The papillary carcinoma is a well-differentiated and relatively common thyroidal cancer. In spite of its characteristics, this neoplasia may be massive or minimally invasive. Almost 14 variants are known, being the diffuse sclerosal one, one of the most aggressive of them, with much less survival than the classic variant; that is the cause of the importance of its diagnosis.
Case presentation: Female patient aged 43 years, with a size increase of the thyroids, positive fine-needle aspiration biopsy of tumoral cells, papillary carcinoma. A total thyroidectomy was made, finding whitish diffuse areas in both lobes. Microscopically, a papillary carcinoma associated to Hashimoto’s thyroiditis was confirmed, showing remarked fibrosis, plentiful psamoma bodies and lymphovascular invasion.
Conclusion: the diffuse sclerosal papillary carcinoma of thyroids behaves aggressively; that is why its treatment should be consequent with its biological behavior. Diagnosing this variant is the key of the success.


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