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2014, Number 1

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Cuba y Salud 2014; 9 (1)

Necrotic purple in new-born. Case presentation

Pérez GJA, Martínez LO, García FY, Rodríguez RM, Jiménez ASE
Full text How to cite this article

Language: Spanish
References: 12
Page: 45-48
PDF size: 438.69 Kb.


Key words:

newborn, disseminated intravascular coagulation, purpura fulminans.

ABSTRACT

Necrotic purple is not commonly seen in the neonatal period although cases have been described in breast-fed babies. Clinical manifestations are well delimitated, located in pressure zones that develop forming blisters and necrotic eschards quickly resulting in spread intravascular clotting, with high risk of thrombosis, neurological and ophthalmological complications and gangrene. The diagnosis is based on the clinical suspicion and determination of C and S levels of proteins. These proteins have low and variable levels in new-born babies, making the diagnosis difficult. The case shown in this paper is a typical example of the disease, which presented disseminated intravascular clotting, with a quick evolution of the hemorrhage.


REFERENCES

  1. Zamora-González Y, Agramonte O, Rodríguez L. Deficiencia de proteínas C y S: marcadores de riesgo trombótico. Rev cubana de Hematología, Inmunología y Hemoterapia. 2013; 29(1):40-47.

  2. Sola A. Cuidados Neonatales. Descubriendo la vida de un recién nacido enfermo. EDIMED, Madrid, 2012; vol. 1, p. 625-627

  3. Lemus Valera L. Sola A, Golombeck GS. Manual práctico para la toma de decisiones en Hematología Neonatal. EDIMED, 2011;(7):56- 110.

  4. El Beshlawy A, Alaraby I, Abou Hussein H, Abou-Elew HH, Mohamed Abdel Kader MS. Study of protein C, protein S and antithrombin III in newborns with sepsis. Pediatr Crit Care Med;2010;11(1):52-9.

  5. Mitsiakos G, Papaioannou G, Papadakis E, Chatziioannidis E, Karagianni P, Giougi E, et al. Haemostatic profile of full-term, healthy, small for gestational age. Throm Rev. 2009;123(3):476-81.

  6. Ohls RK, Yoder MC, Polin RA,. Hematology, Inmunology and Infectious Diseases: Neonatology questions and controversies. Ed. Saunders Elsevier. 2008.

  7. Meijers JC, Herwald H. Protein C Inhibitor. Semin Thromb Hemost. 2011;37(4):349-54.

  8. Avery G, Fletcher M, MacDonald M. Neonatología, fisiopatología y manejo del recién nacido. Editorial Panamericana 5° ed, 2008:154- 166.

  9. Chuansumrit A, Plueksacheeva T, Hanpinitsak S, Sangwarn S, Chatvutinun S, Suthutvoravut U, et al. Prevalence of subclinical vitamin K deficiency in Thai newborn: relationship to maternal phylloquinone intakes and delivery risk. Arch Dis Child Fetal Neonatal Ed. 2010;95 (2):F104-8.

  10. Cruz M. Tratado de Pediatría. Séptima Edición. Ed Ciencias Medicas, La Habana, 2008;1:180-181

  11. Tripod A, Chantarangkul V. Acquired coagulation disorders: revisited using global coagulation/ anticoagulation testing. B J Haematol. 2009;147(1):77-82.

  12. Bussel JB, Sola-Visner M. Current appropoahes to the evaluation and management of the fetus and neonate whit inmune thrombocytopenia. Semin Perinatol. 2009;33:35-42.




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Cuba y Salud. 2014;9