Ortiz-Maldonado F, Rendón-Macías ME, Bernárdez-Zapata I, Iglesias-Leboreiro J, Arteaga-Mancera MP

Language: Spanish
References: 10
Page: 169-173
PDF size: 137.43 Kb.

ABSTRACT

Preterm premature membrane rupture (PROM) predisposes preterm birth immature infants at high risk of neonatal complications.
Objective: To analyze the postnatal complication of pre-term newborn (PTN) less than 37 gestational weeks (wGA) in relation to time of membrane rupture.
Material and methods: A cohort of PTN from his/her birthday to NICU discharge. Three groups were analyzed: without PROM, PROM within first 18h, and after 18 h of life. The complications reviewed were, respiratory distress syndrome (RDS), neumonia, sepsis, pulmonary hypertension, necrotizing enterocolitis, intraventricular hemorrhage, seizures and hyperbilirrubinemia.
Results: PROM was more frequently in extreme PTN (24-31 wGA 13/29, 44.8%; versus 32-34 wGA 11/31, 35.5%, and versus 35-36 wGA 32/282, 11.4%, p ‹ 0.001). Nine patient had a more than 18h of PROM (2.6%). The PROM was associated with RDS in all PTN (69.2% 36/52 versus 52%, 151/290, p = 0.02), but intraventricular hemorrhage was only associated with PROM in extremely PTN (‹ 32 wGA 4/13 versus 0/16, p = 0.03). There were not differences in the proportion of sepsis, NEC, hyperbilirrubinemia, pulmonary hypertension or seizures in relation with PROM. Five extremely PTN died (three with and two without PROM, p = 0.63). There was not statistical difference among the hospital staying days in relation to PROM, only related with level of immaturity.
Conclusion: PROM was more frequently in PTN ‹ 32 wGA, it is associated with DRS, and intraventricular hemorrhage, but the last only in extremely preterm infant.

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