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Anales Médicos de la Asociación Médica del Centro Médico ABC

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Revista de la Asociación Médica del Centro Médico ABC
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2014, Number 4

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An Med Asoc Med Hosp ABC 2014; 59 (4)

Clinical impact of central nervous system incidental findings in oncologic positron emission tomography/computed tomography scan

Barrientos PAH, García OJR, Murrieta GH, Téliz MMA, Casanova SIE, Vázquez LJ
Full text How to cite this article

Language: Spanish
References: 5
Page: 246-251
PDF size: 368.11 Kb.


Key words:

PET-CT, 18F-FDG, CNS.

ABSTRACT

Background: Positron emission tomography – computed tomography (PET-CT) analyzes whole body function and anatomy. Conventional PET-CT exams include skull base to thigh imaging. Objective: To demonstrate the advantages of including the skull in routine scans. To describe findings and clinical relevance of identifying asymptomatic and non suspected head lesions. Material and methods: Retrolective, observational, transversal study. One year period, reviewing 1,217 scans made in a hybrid PET-CT camera, using 2-fluoro-2deoxy-D-glucose labeled with 18-Fluorine ((18F-FDG) as radiotracer. Results: 1,021 cases were included. 18.3% had positive metabolic and/or anatomical findings in head bed. 31% were relevant (5.6% of the total studied). Conclusions: Finding synchronous brain tumors as well as unique head lesions (metastatic or non malignant) in early stages or subclinical, gives an advantage to the physician for giving early management or changing an established treatment (medical or surgical).


REFERENCES

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  2. Liu Y, Ghesani NV, Zuckier LS. Physiology and pathophysiology of incidental findings detected on FDG-PET scintigraphy. Semin Nucl Med. 2010; 40 (4): 294-315.

  3. Bruzzi JF, Troung MT, Marom EM, Mawlawi O, Podoloff DA, Macapinlac HA et al. Incidental findings on integrated PET/CT that do not acumulate 18F-FDG. AJR Am J Roentgenol. 2006; 187 (4): 1116-1123.

  4. Floeth FW, Sabel M, Stoffels G, Pauleit D, Hamacher K, Steiger HJ et al. Prognostic value of 18F-Fluoroethyl-L-tyrosine PET and MRI in small nonspecific incidental brain lesions. J Nucl Med. 2008; 49 (5): 730-737.

  5. Jacobs AH, Thomas A, Kracht LW, Li H, Dittmar C, Garlip G et al. 18F-Fluoro-L-thymidine y 11C-methylmethionine as markers of increased transport and proliferation in brain tumors. J Nucl Med. 2005; (46): 1948-1958.




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An Med Asoc Med Hosp ABC. 2014;59