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2002, Number 2

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Anales de Radiología México 2002; 1 (2)

In Vivo spectroscopic proton magnetic resonance in the differentation of exacerbation remission multiple sclerosis and secondary progressive cronic multiple sclerosis

Dies SP, Ortíz RJJ, Rojas R, Salgado OP, Reynoso G, Sánchez CJ, Rodríguez A, Barrios FA
Full text How to cite this article

Language: Spanish
References: 7
Page: 397-402
PDF size: 418.00 Kb.


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ABSTRACT

In this paper we study multiple sclerosis (MS) by means of spectroscopic quantitative techniques with proton magnetic resonance. This technique is important because it allows quantification of some of the principal metabolites in the central nervous system. It is known that in MS exist a specific concentration of metabolites directly related to the disease. In the study we first measured the metabolites in a control group of healthy individuals, and then compared them with measures taken from a group of patients with MS. To this day we have a control group of 24 individuals, and 2 patients of MS, and the objective is to continue studying more patients with the disease.


REFERENCES

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  2. Govindaraju V, Young K, Maudsley A. Proton nmr chemical shifts and coupling constants for bain matabolites. NMR in Biomedicine, 13:129-153, 2000.

  3. Cucurella MG, Rovira A, Río J, Pedraza S, Tintoré MM, Montalbán X, Alonso J. Proton magnetic resonance spectroscopy in primary and secondary progressive multiple sclerosis. NMR in Biomedicine, 13:57-63, 2000.

  4. Pfefferbaum A, Adalsteinsson E, Spielman D, Sullivan E, Lim K. In vivo spectroscopic quantification of the nacetyl moiety, creatine and choline from large volumes of brain gray and white matter: Effects of normal aging. Magnetic Resonance in Medicine, 41:276-284, 1999.

  5. Schirmer T, Auer DP. On the reliability of quantitative clinical magnetic resonance spectroscopy of the human brain. NMR in Biomedicine, 13:28-36,2000.

  6. Brooks WM, Friedman SD, Stridley CH . Reproducibility of 1h-mrs in vivo. Magnetic Resonance in Medicine, 41:193-197, 1999.

  7. Prorok RJ, Sawyer AM. Fast Imaging Techniques, Signa Advantage Applications Guide, volume IV E8804DC. G.E. Medical Systems, Milwaukee, U.S.A., 1992.




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Anales de Radiología México. 2002;1