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2014, Number 3

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Gaceta Médica Espirituana 2014; 16 (3)

Multiple system atrophy. A case report

Pérez RM, Álvarez GT, Lezcano PY, Tahir SM, Valdivia CS

Language: Spanish
References: 12
Page:
PDF size: 108.28 Kb.


ABSTRACT

Background: The multiple system atrophy is a sporadic neurodegenerative disorder that may begin around age 60 and causes progressive disability to total dependence on a caregiver. Case report: A case presentation of a 57 year-old man who started with signs of unsteady gait and clumsiness in performing daily activities and which was interpreted as Parkinson's disease with poor response to levodopa with benserazide. During his study the patient showed worsening neurological symptoms and a computerized tomography of the skull was performed corroborating head and front cerebellar atrophy which supported the diagnosis of multiple system atrophy type C. He received treatment with levodopa together benserazide, and amantadine and a symptomatic relief of orthostatic hypotension was observed. Conclusions: Early diagnosis of the disease was hindered by its similar onset to other neurodegenerative diseases and its evolution caused progressive loss of the patient´s walking ability and the treatment did not modify the course of the disease.


REFERENCES

  1. Recio M, Navarro S, Espejo B, Mangas C, García R. Signo de la cruz (hot cross bun sign) en la atrofia multisistémica. A propósito de 3 casos. Neurología [Internet]. 2012 Jun [citado en: Ene 2014];27(5):314-5. Disponible en: http://zl.elsevier.es/es/revista/neurologia-295/signo-cruz-hot-cross-bun-sign-atrofia-90138635-cartas-al-editor-2012

  2. Duarte-Martín JJ, Riveira-Rodríguez M. Último minuto en atrofia multisistémica. Rev Neurol [Internet]. 2012 [citado: Ene 2014];54 (Supl. 4):S45-S51. Disponible en: http://www.revneurol.com/sec/resumen.php?i=e&id=2012516

  3. O'Sullivan SS1, Massey LA, Williams DR, Silveira-Moriyama L, Kempster PA, Holton JL, Revesz T, et al. Clinical outcomes of progressive supranuclear palsy and multiple system atrophy. Brain [Internet]. 2008 May [citado: Ene 2014];131(Pt 5):1362-72. Available from: http://brain.oxfordjournals.org/content/131/5/1362.long

  4. Soto A. Presentación de un caso clínico de atrofia multisistémica y actualización de criterios diagnósticos. Rev Cubana Med [Internet]. 2011 Jul-sep [citado: Ene/2014];50 (3). Disponible en: http://scielo.sld.cu/scielo.php?pid=S0034-75232011000300010&script=sci_arttext

  5. Loh KB, Rahmat K, Lim SY. A Hot Cross Bun sign from diffusion tensor imaging and tractography perspective. Neurol India [Internet]. 2011 Mar-Apr [citado: Ene/2014];59(2):266-9. Available from: http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2011;volume=59;issue=2;spage=266;epage=269;aulast=Loh

  6. Sitburana O, Ondo WG. Brain magnetic resonance imaging (MRI) in parkinsonian disorders. Parkinsonism Relat Disord [Internet]. 2009 Mar [citado: Ene/2014];15(3):165-74. Available from: http://www.prd-journal.com/article/S1353-8020%2808%2900144-2/abstract

  7. Jecmenica-Lukic M, Poewe W, Tolosa E, Wenning GK. Premotor signs and symptoms of multiple system atrophy. Lancet Neurol [Internet]. 2012 Apr [citado: Ene/2014];11(4):361-8. Available from: http://www.thelancet.com/journals/laneur/article/PIIS1474-4422%2812%2970022-4/fulltext

  8. Gilman S, Wenning GK, Low PA, Brooks DJ, Mathias CJ, Trojanowski JQ, et al. Second consensus statement on the diagnosis of multiple system atrophy. Neurology [Internet]. 2008 Aug [citado: Ene/2014];71(9):670-6. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676993/

  9. Pereiro I, Arias M, Requena I. Signo de santiaguiño en la atrofia multisistémica. Neurologia [Internet]. 2010 Jun [citado: Ene/2014];25(5):336-7. Available from: http://zl.elsevier.es/es/revista/neurologia-295/articulo/signo-santiaguino-atrofia-multisistemica-13153819

  10. Torres L, Guevara EA, Erick Alberto, Cosentino C. Características clínicas de la atrofia multisistémica: un análisis de 17. Diagnóstico [Internt]. 2010 Ene-mar [citado:Ene/ 2014];49(1):5-11. Disponible en: http://www.fihu-diagnostico.org.pe/revista/numeros/2010/ene-mar/5-10.html

  11. Tha KK1, Terae S, Yabe I, Miyamoto T, Soma H, Zaitsu Y,et al. Microstructural white matter abnormalities of multiple system atrophy: in vivo topographic illustration by using diffusion-tensor MR imaging. Radiology [Internet]. 2010 May [citado: Ene/2014];255(2):563-9. Available from: http://pubs.rsna.org/doi/abs/10.1148/radiol.10090988?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

  12. Nair SR1, Tan LK, Mohd Ramli N, Lim SY, Rahmat K, Mohd Nor H. A decision tree for differentiating multiple system atrophy from Parkinson’s disease using 3-T MR imaging. Eur Radiol [Internet]. 2013 Jun [citado: Ene/2014];23(6):1459-66. Abailable from: http://link.springer.com/article/10.1007%2Fs00330-012-2759-9




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