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Pediatría de México

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Confederación Nacional de Pediatría de México, A. C. (CONAPEME)
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2013, Number 3

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Pediatr Mex 2013; 15 (3)

Light emitted diode (LED) in the treatment of neonatal hyperbilirubinemia. A prototype for phototherapy made in Mexico at low cost

Ávila RR, Suárez LBA, Pérez ACE, Yunes ZJLM, Herrera PM, Hernández MOI, Camacho RRI, Velázquez QNI
Full text How to cite this article

Language: Spanish
References: 9
Page: 73-79
PDF size: 211.93 Kb.


Key words:

Blue LED phototherapy, hyperbilirubinemia, newborns.

ABSTRACT

Introduction: Different types of phototherapy for hyperbilirubinemia used; white and blue fluorescent tubes, halogen light, fiber optic, and light emitting by diode (LED), all meet the recommendations of the American Academy of Pediatrics (30 μW/cm2/nm irradiation and wavelength of 460 to 490 nm). Use innovated a light panel high brightness blue LED to use as phototherapy, which was able to be effective as existing phototherapy devices.
Material and methods: Phototherapy was used in three groups; phototherapy with blue fluorescent light (G-I), fiber optic (G-II) and the LED panel with blue light (G-III). 15 infants was included in each group with phototherapy criteria, was measured bilirubin levels at baseline, 24, 48 and 72 hours of treatment. We compare the results of bilirubin decline in each group.
Results: The G-I, G-II and G-III had an average 20.40 mg/dL, 13.69 mg/dL and 15.45 mg/dL (p = 0.004) at baseline. The average at 24 hours G-I 16.91 mg/dL, G-II 10.77 mg/dL and G-III 11.09 mg/dL (p = 0.003). After 48 hours, the average was G-I 13.43 mg/dL, G-II 8.69 mg/dL and G-III 9.62 mg/dL, (p = 0.004). At 72 hours the average was G-I 9.75 mg/dL, G-II 7.45 mg/dL and G-III of 9.93 mg/dL (p = 0.42).
Discussion: The three types of phototherapy were able to decrease the levels of bilirubin. The LED panel was better than the fluorescent blue light and equal than the fiber optic. With the above managed to get a blue LED phototherapy lamp effective in reducing bilirubin levels at low cost.


REFERENCES

  1. Lauer BJ, Spector ND. Hyperbilirubinemia in the newborn. Pediatr Rev. 2011; 32 (8): 341-349.

  2. Seidman DS, Moise J, Ergaz Z, Laor A, Vreman HJ, Stevenson DK et al. Prospective randomized controlled study of phototherapy using blue and blue-green light emitting devices and conventional halogen-quartz phototherapy. J Perinatol. 2003; 23 (2): 123-127.

  3. Bhutani VK, Committee on Fetus and Newborn. Phototerapy to prevent severe neonatal hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2011; 128 (4): e1046-e1053.

  4. Blanco SM. Comparativa de equipos de fototerapia basados en LEDs. En: XV Seminario de Ingeniería Biomédica 2006. Uruguay: Facultades de Ingeniería y Medicina Universidad de la O. del Uruguay; 2006.

  5. American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the new born infant 35 or more week of gestation. Pediatrics. 2004; 114 (1): 297-316.

  6. Wong RJ, Stevenson D. Treatment of unconjugated hyperbilirubinemia in term and nearterm infant [Internet]. Up to Date. 2007. Topic 5063 Version 23.0. Available in: http://www.uptodate.com/contents/treatment-of-unconjugated-hyperbilirubinemia-in-term-and-late-preterm-infants.[Acceso 08.03.2014].

  7. Maisels MJ, Watchko JF. Treatment of jaundice in low birthweight infants. Arch Dis Child Fetal Neonatal. 2003; 88 (6): 459-463.

  8. Sarin M, Dutta S, Narang A. Randomized controlled trial of compact fluorescent lamp versus standard phototherapy for the treatment of neonatal hyperbilirubinemia. Indian Pediatrics. 2006; 43 (7): 583-590.

  9. Viau CJ, Rountree C, Destarac MA, Cui Y, Pérez M, Herrera M et al. Prospective randomized controlled study comparing low-cost led and conventional phototherapy for treatment of neonatal hyperbilirubinemia. J Trop Pediatr. 2012; 58 (3): 178-183.




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Pediatr Mex. 2013;15