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Órgano Oficial de la Asociación Dental Mexicana

2014, Number 6

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Rev ADM 2014; 71 (6)

Effects of collagen-polyvinylpyrrolidone on bone regeneration following retained third molar surgery. A controlled clinical study.

Macías-Hernández SI, González-Muñoz CG, Ortega-Martín del Campo J, Morones-Alba JD

Language: Spanish
References: 14
Page: 280-284
PDF size: 232.60 Kb.


ABSTRACT

Background: Retained third molar surgery is the most common surgical procedure performed on the oral cavity. Retention, which has a high incidence among young people, carries a risk of pathologies such as lytic lesions, infectious processes, cysts, tumors, and temporomandibular dysfunction. Objectives: To evaluate bone regeneration after the placement of collagen-polyvinylpyrrolidone in the alveolar spaces resulting from the extraction of third molars. Material and methods: We performed a randomized double-blind controlled clinical study involving patients with retained third molars, who were randomly assigned either to an experimental group treated with collagen or to a control group. Preoperative clinical and radiographic assessment was performed at 8 days and one month after surgery. Bone regeneration was evaluated on the basis of radiological progression on panoramic radiographs. Student’s t tests and χ2 tests were carried out to compare the groups. Results: A total of 30 subjects and 86 teeth (43 per group) were included in the study. In terms of pain, differences between the groups were evident at 8 days (p = 0.05). Bone regeneration at 8 days was partial in 44% versus 67% (experimental group versus control group, p = 0.093). At the monthly evaluation, complete regeneration had been achieved in 98% versus 90% (experimental versus control, p = 0.03). A comparison of the radiological progression between the groups showed that significant differences were achieved in the experimental group (p = 0.0001), though not in the control group (p = 0.07). Conclusions: Collagen-PVP is an osteogenic biomaterial that produces bone regeneration in less time than occurs physiologically. Studies are needed to monitor medium- and long-term results, using more sensitive evaluation methods.


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