Camacho RRI, Ávila Reyes Ricardo, Sánchez ZMH, Guerrero MNA, Brussollo CR, Herrera PM, Velázquez QNI, Morris GCG

Language: Spanish
References: 11
Page: 155-159
PDF size: 132.90 Kb.

ABSTRACT

Introduction. The dengue virus is a member of the Flaviviridae family with four serotypes (DEN -1, DEN -2, DEN -3, DEN -4). Causes epidemic outbreaks in endemic areas among adult and pediatric population. Vertical transmission is rare, it is necessary immune positivity in the mother and newborn for confirmation.
Case report. A 37 week pregnant female with dengue fever confirmed by positive rapid test NS1 IgM positive. At 39 weeks a male infant is obtained by cesarean section, at 48 hours of life test reports for dengue IgM are positive, IgG negative and positive NS1, as well as thrombocytopenia. He was referred to a tertiary hospital where platelets were closely monitored to normality at the 10th day of day of life and was discharged. NS1 and IgM were confirmed positive identified by real-time RT PCR DENV -1.
Discussion. Vertical transmission of dengue is rare, the incidence is reported in 1.6% Vertical dengue infection has been described in series of isolated cases. In recent years the vertical transmission of dengue with severe effects on both the fetus and the newborn is reported. Controversy exists over whether the dengue virus is vertically transmitted or not. The confirmation requires the presence of specific IgG and IgM in both the mother and the NB or viral isolation in neonatal peripheral blood or placental viral identification. This case developed asymptomatic thrombocytopenia.

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