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Perinatología y Reproducción Humana

ISSN 0187-5337 (Print)
Instituto Nacional de Perinatología
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2014, Number 3

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Perinatol Reprod Hum 2014; 28 (3)

The development of gynecobstetric endocrinology at the Instituto Mexicano del Seguro Social

Zárate A, Hernández-Valencia M
Full text How to cite this article

Language: Spanish
References: 9
Page: 174-177
PDF size: 243.75 Kb.


Key words:

Gynecologic endocrinology, perinatology, hormones.

ABSTRACT

Dr. Luis Castelazo Ayala had succeeded in turning the Gabriel Mancera Maternity Hospital into the Hospital of Obstetrics and Gynecology No. 1 (HGO 1), but he wanted it to be regarded as a center of scientific excellence with both domestic and international prestige, so it became essential to add scientific medicine to obtain academic credit. Thus, a laboratory was implemented to do some hormonal tests on urine, which later sustained the scientific medical research of gynecological endocrinology and the implementation of hormonal determinations with the novel technique of radioimmunoassay. Rudimentary laboratory tests that supplemented those traditionally used were also made to determine the degree of fetal development. Estriol and phospholipids measurements were the most common; they also helped to decide upon the use of glucocorticoids to improve lung immaturity. The HGO 1 was relocated to the south of the city, which contributed to modernize and improve the high specialty laboratories and to create the Department of Perinatology, which resulted in a boost to the research in the areas of perinatology and postpartum endocrinology. This included the physiology and pharmacological manipulation of breastfeeding and of the hypothalamus-adenohypophysis-ovary axis. This resulted in several publications related to the areas of diagnosis and therapy of hormonal dysfunctions in the physiological stages of puberty, gestation and puerperium.


REFERENCES

  1. Zárate A. Panorama de la investigación médica en el Instituto Mexicano del Seguro Social. Rev Med IMSS. 1984; 22: 229-36.

  2. Zárate A. Notas históricas sobre la investigación científica en el IMSS. En: Echevarría S, Lifshitz A, Salamanca S. La reforma de la investigación en el IMSS. México; 2012. pp. 17-30.

  3. Schally AV. Some notes on the background of the isolation, determination of structure, synthesis, and early clinical trials of the luteinizing hormone and follicule stimulating hormone releasing hormone. Am J Obtest Gynecol. 1976; 125: 1142.

  4. Kastin AJ, Zárate A, Midgley AR, Canales ES, Schally AV. Ovulation confirmed by pregnancy after infusion of porcine LH-RH. J Clin Endocrinol Metab. 1971; 33: 980-2.

  5. Zárate A, Canales ES, Soria J, Ruiz F, MacGregor C. Ovarian refractoriness during lactation in women. Effect of gonadotropin stimulation. Amer J Obstet Gynec. 1972; 112: 1130-5.

  6. Canales ES, Zárate A, Garrido J, León C, Soria J, Schally AV. Studies on the recovery of pituitary FSH function during puerperium using synthetic LRH. J Clin Endocrinol Metab. 1974; 38: 1140-5.

  7. Zárate A, Canales ES, Alger M. The effect of pregnancy and lactation on pituitary prolactin secreting tumors. Acta Endocrinol. 1979; 92: 407-12.

  8. Barquin M, Méndez-Cervantes F. Historia Gráfica de la Medicina. 3ª ed. México: Méndez Editores; 2013.

  9. De la Fuente JR, Martuscelli J, Alarcón D. La investigación en salud: balance y transición. Biblioteca de la Salud. México: Fondo Cultura Económica; 1990.




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C?MO CITAR (Vancouver)

Perinatol Reprod Hum. 2014;28