2014, Number 2
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ABSTRACTThe biological functions and pharmacological properties of epidermal growth factor have been the subject of intensive research and numerous scientific publications, especially regarding its role in scar formation.
This is the report on a systematic review of an extensive online database to identify literature relevant to the field of dermatology.
Berlanga-Acosta J, Gavilondo-Cowley J, García D, Martín-Machado J, Guillen-Nieto G. “Epidermal Growth Factor (EGF) and Platelet-Derived Growth Factor (PDGF) as Tissue Healing Agents: Clarifying Concerns about their Possible Role in Malignant Transformation and Tumor Progression”. J Carcinogene Mutagene 2011; 1: 3-11.
Viswanathan V, Pendsey S. “A phase III study to evaluate the safety and efficacy of recombinant human epidermal growth factor (REGEN-DTM 150) in healing diabetic foot ulcers”. Wounds. 2006; 18: 186-196. ana maría gama méndez y cols. f a c t o r de c r e c imi e n t o e p idé rmi co Dermatología Cosmética, Médica y Quirúrgica DCMQ 132 A R T Í C U L O S D E R E V I S I Ó N Volumen 12 / Número 2 n abril-junio 2014
Fernández-Montequin J, Valenzuela-Silva C, Gonzalez-Silva O, Savigne W, Sancho-Soutelo L, Rivero-Fernandez F, et al. “Intralesional injection of recombinant human epidermal growth factor promote granulation and healing in advanced diabetic foot ulcer: a multicenter, randomized, placebo-controlled, double-blind study”. Int Wound J 2009; 6: 432-443.