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2014, Number 5

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Rev Invest Clin 2014; 66 (5)

Comparison of free κ and λ light chain immunoassays and total (bound and free) κ and λ light chain immunoassays

Delgado F, Kuus K
Full text How to cite this article

Language: English
References: 5
Page: 473-474
PDF size: 94.73 Kb.


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ABSTRACT

We read, with interest, the article by Dr. Zamora- Ortiz, et al. Poor performance of the total kappa/ lambda light chain quantification in the diagnosis and follow-up of patients with multiple myeloma on the comparison of the total serum light chain assay (sLC), SPE and IFx for screening patients with a suspected plasma cell disorder.


REFERENCES

  1. Zamora-Ortiz F, Velázquez-Sánchez-de-Cima S, Hernández- Reyes J, Martagón-Herrera NA, Ruiz-Argüelles A, Ruiz-Delgado G, Ruiz-Argüelles G-J. Poor performance of the total kappa/lambda light chain quantification in the diagnosis and follow-up of patients with multiple myeloma. Rev Invest Clin 2014; 66(4): 314-18.

  2. Kyle RA. Sequence of testing for monoclonal gammopathies. Arch Pathol Lab Med 1999; 123(2): 114-8.

  3. Gertz MA, Comenzo R, et al. Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004. Am J Hematol 2005; 79(4): 319-28.

  4. Durie BG, Harousseau JL, et al. International uniform response criteria for multiple myeloma. Leukemia 2006; 20(9): 1467-73.

  5. Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R, Palumbo A, et al. International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders. Leukemia 2009; 23(2): 215-24.




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Rev Invest Clin. 2014;66