Cabrera HN, Carriquiri MF, Griffa EM, García S

Language: Spanish
References: 4
Page: 16-18
PDF size: 157.66 Kb.

ABSTRACT

Background: Nevus are localized skin malformations. Melanotic nevus can be acquired (common melanotic nevi) or inherited; they can also appear in syndromes such as neurofibromatosis with the café au lait macules.
Objectives: To report a clinical feature of the melanotic nevus that could help with its diagnosis when seen in other syndromes.
Methods: We studied 10 patients with melanotic nevus, and 5 with neurofibromatosis type 1, with 45 café au lait macules.
Results: Every patient with melanotic nevus showed a prolongation of the macule similar to spread ink (the sign of spread ink). None of the 45 café au lait macules of the 5 patients with neurofibromatosis type I presented this sign.
Conclusions: We consider that the appearance of this clinical feature, “sign of spread ink”, makes the diagnosis of melanotic nevi easier, by ruling out the café au lait macule of the neurofibromatosis.

REFERENCES

1. Cabrera H, García S. “Nevos Despigmentarios”. En Nevos, 1ª Ed. Argentina, Actualizaciones Médicas SRL, Bs.As. 1998.

2. Cabrera H, Della Giovanna P, Hermida D. “Syndromic Nevoid Hyperrmelanosis Description of 7 cases with a 10 year follow up”. J Dermatol 2011 Feb; 138(2): 125-30.

3. Riccardi VM. “The multiple forms of neurofibromatosis”. Pediatr Rev 1982; 31: 293.

4. Della Giovanna P, Cabrera HN. “Neurofibromatosis segmentaria”. Arch Argent Dermatol 1991; 4: 171.