2007, Number 4
Dermatología Cosmética, Médica y Quirúrgica 2007; 5 (4)
Rebollo DN, Gutiérrez MD, Fonte AV, Vega ME
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ABSTRACTScleroderma, or morphea, is a chronic connective tissue disease which is characterized by sclerosis of the skin caused by excessive production of collagen. Morphea is more prevalent in women during the second and third decade. The most common type is plaque morphea. Clinically it is characterized by hyperpigmented plaques with an eythematous border during the active phase, that turn sclerotic, alopecic and anhidrótic as the disease progresses. The etiology is unknown, but genetic, infectious, traumatic and immunologic factors have been implicated. Even though it is an asymptomatic and autolimited disease, the aesthetic and functional deformities urge patients to seek treatments which at this time are unsatisfactory.