Delgado GAF, Valdés RYC, Polo VJC, Marcel EA

Language: Spanish
References: 13
Page: 40-45
PDF size: 320.42 Kb.

ABSTRACT

Evidence-based medicine associates globalization with the phenomenon of nutritional transition, and this, as the promoter of the origin and epidemiological expansion of noncommunicable diseases (NCDs) in all groups of ages; particularly, coronary atherosclerotic disease (CAD), which begins from the childhood and in which origin cholesterol is involved. The objective of this work was to determine the reference ranges of total cholesterol in serum in incoming freshmen of different age groups, as well as the association with their gender. Method: Cross-sectional study to determine the reference intervals levels of [Chol]_T in 192 students of both sexes without familial or personal pathological history who consented to participate in the study. They were distributed by age groups: 17-19, 20-24 and ≥ 25 years, and their habits of consumption of fast foods and alcohol were recorded. The serum from 5 mL of blood collected by venipuncture was isolated to determine the levels of [Chol]_T by an enzymatic method. We used the software SPSS version 21, for a 0.05 of significance, for the statistical processing of the results and establishment of reference intervals of the [Chol]_T for age group and its association with sex. Results: The distribution of the values of [C]_T, was significant (p ‹ 0.05) for age and sex. Three reference intervals were determined according to age: 138-146 mg/dL for 17-19 years; 141-158 mg/dL for 20-24 years and 151-177 mg/dL for ≥ 25 years. Discussion: According to the criteria of ATPIII, the RI set for those groups younger than 25 years are acceptable, while in students older than ≥ 25 years, the upper limit exceeds 170 mg /dL.

REFERENCES

1. Alwan A et al. Monitoring and surveillance of chronic non communicable diseases: progress and capacity in high-burden countries. Lancet. 2010; 376: 1861-1868.

2. Alwan A. Informe sobre la situación mundial de las enfermedades no transmisibles 2010 Resumen de orientación. Ginebra: Organización Mundial de la Salud, 2011.

3. Bloom DE et al. The global economic burden of non-communicable diseases World Economic Forum. Harvard School of Public Health, Geneva, 2011.

4. OMS. Informe sobre la situación mundial de las ENT 2010. Resumen de orientación.

5. Moráis A, Lama More-RA. Hipercolesterolemia. Abordaje terapéutico. An Pediatr (Barc). 2009; 70: 488-496.

6. National Education Cholesterol Program. Report of the expert panel on blood cholesterol levels in children and adolescent. Pediatrics. 1992; 89: 525-583.

7. Kanani PM, Sperling MA. Hiperlipidemias in adolescents. Adolescent Med. 2002; 13: 37-522.

8. Valente AM, Newburger JW, Lauer RM. Results of expert meetings: conducting pediatric cardiovascular trials. Hiperlipidemias in children and adolescents. Am Heart J. 2001; 142: 433-439.

9. Savino P. Obesidad y enfermedades no transmisibles relacionadas con la nutrición. Rev Colomb Cir. 2011;26:180-195.

10. Pasca AJ, Pasca L. Transición nutricional, demográfica y epidemiológica. Determinantes subyacentes en las enfermedades cardiovasculares. Insuf Card. 2011; 6 (1): 27-29.

11. Sáez Y, Bernui I. Prevalencia de factores de riesgo cardiovascular en adolescentes de instituciones educativas. An Fac Med. 2009; 70 (4): 259-265.

12. Organización Mundial de la Salud. Serie de informes técnicos: dieta nutrición y prevención de enfermedades crónicas. Ginebra: OMS; 2003.

13. Morales GI, del Valle C, Soto A, Ivanovic D. Factores de riesgo cardiovascular en estudiantes universitarios. Rev Chil Nutr. 2013; 40 (4): 391-396.