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Revista ADM Órgano Oficial de la Asociación Dental Mexicana

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Órgano Oficial de la Asociación Dental Mexicana
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2015, Number 1

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Rev ADM 2015; 72 (1)

Central giant cell lesion: A case report and review of the literature.

Liceága EJC, Montoya PLA, Aldape BBC, Vélez CME, Arenillas LJ, Ojeda JL
Full text How to cite this article

Language: Spanish
References: 11
Page: 48-53
PDF size: 357.13 Kb.


Key words:

Giant cells, hyperparathyroidism, treatment.

ABSTRACT

The central giant cell lesion (CGCL) is a rare benign intraosseous lesion of the jawbone that can prove to be aggressive. While its etiology is open to question, it is more frequent in young women and the molar and premolar region of the mandible. Surgical or combined treatment is preferred. We describe the case of a 19-year-old patient that sought treatment for swelling in the mid- and lower-third of her face that had developed over a period of three months, accompanied by pain and tooth mobility. Clinical and imaging studies were performed along with an incisional biopsy for histopathological assessment, which resulted in confirmation of the diagnosis of CGCL. Laboratory tests revealed normal levels of calcium, alkaline phosphatase, and parathormone, so ruling out the possibility of a brown tumor of hyperparathyroidism. Surgical treatment was performed, consisting of curettage and peripheral ostectomy under general balanced anesthesia, and the extraction of the teeth concerned.


REFERENCES

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  2. Portelles AM, Heredia JM. Granuloma central de células gigantes. Rev Cubana Estomatol. 2011; 48 (1): 84-88.

  3. Valentine JC, Nelson BL. Central giant cell lesion. Head and Neck Pathol. 2011; 5: 385-388.

  4. Jadu FM, Pharoah MJ, Lee L, Baker GI, Allidina A. Central giant cell granuloma of the mandibule condyle: a case report and review of the literature. Dentomaxillofac Radiol. 2011; 40: 60-64.

  5. Yuzbasioglu E, Alkan A, Özer M, Bayram M. Multidisciplinary approach for the rehabilitation of central giant cell granuloma: a clinical report. Niger J Clin Pract. 2014; 17 (4): 528-533.

  6. Regezi JA, Sciubba JJ. Patología bucal: correlaciones clinicopatológicas. 3a ed. México, McGraw-Hill Interamericana; 2000.

  7. da Silva NG, Dias AS, Nelo E, Mesquita F, López K, Viana J de J. Treatment of central giant cell lesions using biphosphonates with intralesional corticosteroid injections. Head Face Med. 2012; 8: 23.

  8. Argao M de S, Ramalho R de A, Pereira FA, Regadas C, Dias-Ribeiro E, Ferreira J. Evaluación de las modalidades terapéuticas para la lesión central de células gigantes: revisión de la literatura. Acta Odontol Venez [Internet]. 2012 [citado Jul 6 2014]; 50 (2). Disponible en: http://www.actaodontologica.com/ediciones/2012/2/art18.asp

  9. Selvi F, Cakarer S, Tanakol R, Guler SD, Keskin C. Brown tumour of the maxilla and mandible: a rare complication of tertiary hyperparathyroidism. Dentomaxillofac Radiol. 2009; 38: 53-58.

  10. Reséndiz JA, Alvarado I, Flores R, Hernández M, Barroso S, Gómez F et al. Múltiples tumores pardos maxilofaciales como manifestación de hiperparatiroidismo primario. Gac Med Mex. 2008; 144 (2): 155-160.

  11. Nogueira RLM, Teixeira RC, Cavalcante RB, Ribeiro RA, Rabenhorst SHB. Intralesional injection of triamcinolone hexacetonide as an alternative treatment for central giant-cell granuloma in 21 cases. Int J Oral Maxillofac Surg. 2010; 39: 1204-1210.




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Rev ADM. 2015;72