medigraphic.com
SPANISH

Revista Cubana de Investigaciones Biomédicas

ISSN 1561-3011 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2014, Number 2

<< Back Next >>

Rev Cubana Invest Bioméd 2014; 33 (2)

Plasma creatinine, glomerular filtration and blood pressure in children with low birth weight due to intrauterine growth retardation

Espinosa SI, Pérez RA, Barber FMO, García SJ
Full text How to cite this article

Language: Spanish
References: 15
Page: 161-167
PDF size: 92.33 Kb.


Key words:

intrauterine growth retardation, hypertension, kidney.

ABSTRACT

Introduction: Low birth weight due to intrauterine growth retardation (IUGR) may induce renal function modifications leading to arterial hypertension.
Objective: assess blood pressure in normotensive children with a personal history of low birth weight due to IUGR.
Methods: a study was conducted of plasma creatinine, glomerular filtration and blood pressure in 19 normotensive children aged 4-5 years with a history of low birth weight due to IUGR (Group 1: IUGR) and their controls (Group 2: Controls).
Results: a lower plasma creatinine concentration was found in Group 1 (0.691 vs. 0.751) with p=0.001*, whereas similar values were found for blood pressure (80.0 vs. 78.5) and glomerular filtration intensity (86.1 vs. 83.4) with p‹0.05.
Conclusions: renal function modifications occurring before the study period may not be discarded.


REFERENCES

  1. Alfonzo Guerra JP. Obesidad. Epidemia del siglo XXI. Ed. Científico-Técnica 2008,4:50-61.

  2. World Health Report 2002: Reducing risks, promoting healthy life. Geneva, Switzerland: World Health Organization. 2002. Disponible en: URL: http://www.who.int/whr/2002/. [Consulta: 6 agosto 2009].

  3. Alfonzo Guerra JP. Hipertensión arterial en atención primaria de salud. La Habana: Editorial Científico-Técnica;2010.

  4. David J.P. Barker. Birth Weight and Hypertension David J.P. Barker. Hypertension. 2006;48:357.

  5. Eriksson JG, Forsen TJ, Kajantie E, Osmond C, Barker DJP. Childhood Growth and Hypertension in Later Life. Hypertension 2007;49:1415-142.

  6. Luyckx VA , Brenner BM . Low birth weight, nephron number, and kidney disease. Kidney Int Suppl 2005;(97):S68-S77.

  7. Mendoza C. Importancia ético-científica de los protocolos sobre las investigaciones en seres humanos. Med.leg.Costa Rica [revista en la Internet]. 2003 Mar [citado 2011 Mar 28];20(1):37-42. Disponible en: http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1409-00152003000100005&lng=es

  8. Hipertensión arterial. Guía para la prevención, diagnóstico y tratamiento/ Comisión Nacional Técnica Asesora del Programa de Hipertensión arterial. La Habana: Editorial Ciencias Médicas 2008;36-38.

  9. Schwartz GJ, Haycock GB, Edelman CM y Spitzer A. A simple estimate of glomerular filtration rate in children derived form body lenght and plasma creatinine. Pediatrics 1976; 58:259-263.

  10. Hecht K. Hipocamp role in experimental neurosis. Neurotic disregulation of the blood pressure in: Physyological theatrical and practical aspect in psiquiatric. La Habana. Editorial Científico Técnica, 1979.

  11. B. Argüelles. Valores de referencia de urea, creatinina y aclaramiento de creatinina en niños adolescentes. Nefrología 1994;(2):88-90.

  12. Luyckx V.A. and Brenner B.M. The Clinical Importance of Nephron Mass.J. Am. Soc. Nephrol; 1, 2010; 21(6):898-910.

  13. Manning, J, Beutler, K, Knepper, M. A. and Vehaskari, V. M. Upregulation of renal BSC1 and TSC in prenatally programmed hypertension. Am. J. Physiol. Renal Physiol 2002; 283: F202-F206.

  14. Erich Cosmi. Consequences in Infants That Were Intrauterine Growth Restricted. Journal of Pregnancy 2011; Article ID 364381: 6 pages. doi:10.1155/2011/364381

  15. Brenner and Rectors. The kidney 6thed. edited Barry M Brenner 2000;(1):1129.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Cubana Invest Bioméd. 2014;33