2015, Number 1
Candida urinary tract infections. An open study in 29 cases in a general hospital
Vega-Sánchez DC, Bernal-López LE, Villanueva-Recillas S, Arenas GR
Full text
Language: Spanish
References: 11
Page: 19-24
PDF size: 436.36 Kb.
ABSTRACT
Background: Candidiasis is caused by Candida spp. Clinical manifestations are related to the immune response of the host; 11% of urinary tract infections are caused by Candida sp and the urinary catheter is the main risk factor for the renal involvement by hematogenous spread. Clinical manifestations are similar to bacterial infections, characterized by malaise, fever, abdominal and low back pain. Renal failure is a complication secondary to the obstruction of the urinary tract by fungal material, with subsequent anuria (urine output ‹50mL/day) and renal failure.Objective: To identify Candida urinary infections in hospitalized patients, as well as the most common predisposing factor for this comorbidity at General Hospital Dr. Manuel Gea Gonzalez, Mexico City.
Material and method: A retrospective, cross-sectional and observational study was performed in 55 hospitalized patients with urinary infection due to Candida spp.
Results: Just 29 patients were included, because complete data was not available in 26. We isolated Candida spp in 29 patients. Species were distributed as follows: Candida spp (n=15), Candida albicans (n=11), Candida tropicalis (n=2) and Candida parapsilosis (n=1). Patients under prolonged antimicrobial treatment were: with monotherapy (n=6), dual therapy (n=3), triple therapy (n=6), quadruple therapy (n=4). The comorbidities were: diabetes mellitus (n=9), chronic renal failure (n=3), arterial hypertension (n=3), malignancy (n=1), cardiovascular disease (n=1), infections (n=3), none (n=8). Surgical procedure: n=16; Foley catheter user: n=22.
Conclusions: Candida albicans remains one of the most common species in urinary infections, most often in women older than 65 years and the most important associated comorbidity is type 2 diabetes.
REFERENCES
Bouza E, San Juan R, Muñoz P, et al, Co-operative Group of the European Study Group on Nosocomial Infections. A European perspective on nosocomial urinary tract infections I. Report on the microbiology workload, etiology and antimicrobial susceptibility (ESGNI-003 study). European Study Group on Nosocomial Infections. Clin Microbiol Infect 2001;7:523-531.