Kably-Ambe A, Carballo-Mondragón E, Durán-Monterrosas L, Soriano-Ortega KP, Roque-Sánchez AM

Language: Spanish
References: 12
Page: 104-109
PDF size: 544.86 Kb.

ABSTRACT

Background: There are many studies showing that more days of sexual abstinence increased sperm concentration, however, the direct influence between the days of abstinence and pregnancy rates has not been evaluated. The usual recommendation is 3-4 days prior to intrauterine insemination; this based on the interval that maximizes the number of motile sperm in the ejaculate. There are some reports with better success rate when abstinence is less than three days.
Objective: To evaluate the pregnancy rate post-intrauterine insemination according to days of sexual abstinence prior to obtaining semen sample.
Patients and methods: A retrospective, observational and transversal study in patients attending the Mexican Center for Fertility (CEPAM) to intrauterine insemination. For analysis patients were grouped by age group, success rate and days of sexual abstinence. Continuous variables are reported as means and standard deviations; to determine statistical significance univariate logistic regression was performed. Categorical variables were evaluated in frequencies and percentages. The calculations were performed using JMP software program.
Results: 3,123 couples were included and increased success rate for intrauterine insemination was obtained with less than seven days of sexual abstinence. The rate of sperm retrieval is inversely proportional to the days of abstinence.
Conclusion: A better pregnancy rate in intrauterine insemination was achieved with less than seven days of sexual abstinence and sperm retrieval rate was also recorded with fewer days of abstinence.

REFERENCES

1. Marshburn PB, Alanis M, Matthews ML, Usadi R, Papadakis MH, Kullstam S, Hurst BS. A short period of ejaculatory abstinence before intrauterine insemination is associated with higher pregnancy rates. Fertil Steril 2010;93:286-8.

2. Elzanaty S, Malm J, Giwercman A. Duration of sexual abstinence: epididymal and accessory sex gland secretions and their relationship to sperm motility. Human Reproduction 2005;20:221-225.

3. Jurema MW, Vieira AD, Bankowski B, Petrella C, Zhao Y, Wallach E, et al. Effect of ejaculatory abstinence period on the pregnancy rate after intrauterine insemination. Fertil Steril 2005;84:678-81.

4. De Jonge Ch, LaFromboise M, Bosmans BSE, Ombelet W, Cox A, Nijs M. Influence of the abstinence period on human sperm quality. Fertil Steril 2004;82:57-65.

5. Gosálvez J, González-Martínez M, López-Fernández C, Fernández JL, Sánchez- Martín P. Shorter abstinence decreases sperm deoxyribonucleic acid fragmentation in ejaculate. Fertil Steril 2011;96:1083-6.

6. Levitas E, Lunenfeld E, Weiss N, Friger M, Har-Vardi I, Koifman A, Potashnik G. Relationship between the duration of sexual abstinence and semen quality: analysis of 9,489 semen samples. Fertil Steril 2005;83:1680-6.

7. Agarwal A, Ramadan A, Saleh M, Bedaiwy A. Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 2003;79:829-43.

8. Van Voorhis BJ, Barnett M, Sparks AE, Syrop CH, Rosenthal G, Dawson J. Effect of the total motile sperm count on the efficacy and cost-effectiveness of intrauterine insemination and in vitro fertilization. Fertil Steril 2001;75:661-8.

9. World Health Organization. Laboratory Manual for the Examination and processing of human semen. 5 th ed, 2010.

10. Sánchez-Martín P, Sánchez-Martín F, González-Martínez M, Gosálvez J. Increased pregnancy after reduced male abstinence. Syst Biol Reprod Med 2013;59:526-60.

11. Lehavi O, Botchan A, Paz G, Yogev L, Klieman SE, Yavetz H, Hauser R. Twenty- four hours abstinence and the quality of sperm parameters. Andrologia 2014;46:640-646.

12. Horvath PM, Bohrer M, Shelden RM, Kemmann E. The relationship of sperm parameters to cycle fecundity in superovulated women undergo-ing intrauterine insemination. Fertil Steril 1989;52:288-94.