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2014, Number 4

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Rev Hosp Jua Mex 2014; 81 (4)

Tumor de células germinales de ovario. Presentación clínica y su tratamiento en 15 casos

Vargas-Hernández VM, Vargas-Aguilar VM, Acosta-Altamirano G, García-Rodríguez FM, Jiménez-Villanueva X, Moreno-Eutimio MA
Full text How to cite this article

Language: Spanish
References: 13
Page: 214-219
PDF size: 130.61 Kb.


Key words:

Malignant germ cell tumors of the ovary, endodermal sinus tumor, immature teratoma, fertility, chemotherapy, radiation therapy, conservative surgery.

ABSTRACT

This is a retrospective, descriptive study of women with histologic diagnostic of malignant tumor or germinal cells done in 15 patients from 1993-1998 in the Oncologic Gynecologic Service of the Hospital Juárez de Mexico: eight were dysgerminomas (53.3%), three (20%) endodermal sinus tumors and four (26.6%) inmature teratomas. The study involves 15 patents (12-32 years average 22 years. Nine (60%) were in early stage (II of FIGO) six (40% were in early stage (III FIGO). Tumoral size 12-20 cm average 16 cm. Main symptoms were: abdominal pain, abdominal distention, and abdominal pelvic tumor. α-fetoprotein was used as tumoral marker for follow-up. Surgical treatment was palliative in 12 (80%), radical in three (20%); 15 patients (100%) received adjuvant chemotherapy on Cisplatin and only 1 patient (6.6%) received radiotherapy; the end of this study 14 women are still alive without evidence of tumoral activity and 1 (6.6%) with endodermal sinus tumor died. Germinal cells tumors have a good prognosis when they have favorable response to chemotherapy which is good in women in fertile age mainly when tumor is in early stage.


REFERENCES

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  3. Armando Quero-Hernández A, Estrada-Correa R, Tenorio- Rodríguez H, Álvarez-Solís RM. Tumor de células germinales de ovario: características clínicas y resultados del tratamiento. Cir Ciruj 2007; 75: 81-5.

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Rev Hosp Jua Mex. 2014;81