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ISSN 1561-3070 (Electronic)

2014, Number 2

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Rev Cub Oftal 2014; 27 (2)

Pseudoexfoliation and cataract

Rodríguez SB, Pérez CEC, Méndez DEAM, Ramos PY, Veitía RZA

Language: Spanish
References: 24
Page: 253-263
PDF size: 159.72 Kb.


ABSTRACT

Pseudoexfoliation syndrome is an age-related generalized fibrotic matrix disorder, which may not only cause chronic open angle glaucoma and cataract, but also a range of other serious spontaneous and surgical intraocular complications. Recent research studies have led to better understanding of effects of the pseudo exfoliation process on ocular tissues by refining diagnostic criteria, applying new therapeutic regimes, and by developing new preventive strategies to reduce surgical complications. The new pathogenetic concepts describe pseudoexfoliation syndrome as microfibrillopathy involving transforming growth factor-B1, oxidative stress, and impaired cellular protection mechanisms. A clinical and surgical evaluation of glaucoma and cataract in patients with pseudoexfoliation was presented in this article.


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