2015, Number 1
Clinical radiological correlation with anatomic-pathologic results of lymphadenectomy in patients with oncologic tongue lesions
Language: Spanish
References: 24
Page: 4-10
PDF size: 215.74 Kb.
ABSTRACT
Objective: The aim of this study was to correlate the anatomopathological findings of lymphadenectomies in patients diagnosed with tongue carcinoma with the preoperative clinical and radiological data obtained through cervical palpation and computed tomography (CT), assessing the predictive capacity of those studies in the detection of lymph node metastasis. Material and methods: A retrospective study of 113 patients diagnosed with lingual neoplasia during the period from 2008 to 2013 by the Oral and Maxillofacial Surgery Department of the Hospital General Universitario Gregorio Marañón. Of these, 66 patients met the inclusion criteria; the rest were excluded. Results: Considering the performed lymph node dissections, histological findings demonstrated tumoral infiltration (N+) in 31.82%. The sensitivity of both the cervical palpation and CT was 76.20%, while the specificity of the cervical palpation and the CT were 77.78% and 80% respectively. Palpation and CT agreed in 72.26% of cases. Both examinations were positive in 35.30% and nodal involvement was demonstrated in 77.78% of these cases through histological findings. Conclusions: The low sensitivity and specificity found in the tests currently protocolized in the detection of metastatic lymph nodes, as well as the high percentage of subclinical neck lymph node metastasis, common in tongue neoplasms, could explain de discordance found in the clinical and histological staging. Consequently, more sensitive and specific tests are needed to enhance the detection of lymphadenopathies. The absence of these exams could explain the prophylactic lymphadenectomies performed.REFERENCES
Ortega P. Actualización en metástasis ganglionar de carcinoma escamoso de cabeza y cuello: disección ganglionar, ganglio centinela y técnicas de biología molecular. Rev Otorrinolaringol Cir Cabeza Cuello [Revista electrónica]. 2008; 68 (1). Disponible en: http://www.scielo.cl/scielo.php?pid=S0718-48162008000100010&script=sci_arttext
Villarreal PM, García-Rozado A, Cebrián JL. Biopsia de los ganglios centinelas cervicales en el carcinoma de células escamosas oral y orofaríngeo. En: SECOM. Protocolos de la Sociedad Española de Cirugía Oral y Maxilofacial [Internet]. España: SECOM; 2014. Disponible en: http://www.secom.org/web/wp-content/uploads/2014/01/cap38.pdf
Córdoba S, Romero J, Valcárcel F, Magallón R, Regueiro CA, García-Berrocal MI et al. Observación frente al tratamiento electivo en cáncer de lengua móvil con cuello clínicamente negativo: resultados de una serie de 243 pacientes. Oncología [Revista electrónica]. 2004; 27 (1). Disponible en: http://scielo.isciii.es/pdf/onco/v27n1/03.pdf
Ng SH, Yen TC, Tun-Chiech J, Chan SC, Ko SF, Wang HM et al. Prospective study of [18F] fluorodeoxyglucose positron emission tomography and magnetic resonance imaging in oral cavity squamous cell carcinoma with palpably negative neck. Magnetic resonante imaging versus clinical palpation in evaluating cervical metastasis from head and neck cancer. J Clin Oncol. 2006; 24 (27): 4371-4376.
Sánchez-Navarro C, Pérez-Lara A, De Hita-Santabaya AI, Daura-Sáez A, Ruiz-Cruces R, Bautista-Ojeda MD. Valor de la resonancia magnética en la medición del espesor tumoral en el cáncer de lengua: correlación del espesor radiológico con el espesor anatomopatológico en una muestra de 15 pacientes. Rev Esp Cir Oral Maxilofac. 2014; 36 (1): 9-14.