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16 de abril

2014, Number 255

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16 de abril 2014; 53 (255)

Aspectos clínicos y epidemiologicos de pacientes con trombofilia primaria. Cardiocentro “Ernesto Che Guevara”. 2011-2014

Casas CY, Iraola LMA, Manresa CY, Carmona M, Aparicio SJL

Language: Spanish
References: 26
Page: 43-54
PDF size: 120.62 Kb.


ABSTRACT

Introduction: Primary thrombophilia is a rare and under-diagnosed disease.
Objective: To characterize clinically and epidemiologically patients with primary thrombophilia treated at the Cardiology Center Ernesto Che Guevara, in the period between September 2011 to February 2014.
Materials and Methods: A cross-sectional, descriptive-observational study with retrospective data search in patients treated at the Cardiology Thrombophilia of Ernesto Che Guevara, during the period September 2011 to February 2014.
Results: The risk factors most frequently identified were hypertension in 19.1%, and obesity with equal frequency in 17% of major surgery. In 98.1% of patients the first thrombotic event occurred before the age of 50 and 75.5% had recurrent thrombosis. 45.2% of patients had primary thrombophilia; in 37.5% of these was determined more than one thrombophilic factor.
Conclusions: Primary thrombophilia was found in almost half of the patients involved in the study, protein S deficiency was the predominant cause, and combined thrombophilia was identified, being the most frequent, the association of protein C and S deficiency.


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