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Acta Médica del Centro

ISSN 1995-9494 (Electronic)
Revista del Hospital Clínico Quirúrgico "Arnaldo Milián Castro"
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2015, Number 1

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Acta Med Cent 2015; 9 (1)

Epigenetics, a new perspective in Medicine

Riera VL, San Miguel PA, Pimienta PN
Full text How to cite this article

Language: Spanish
References: 10
Page: 66-69
PDF size: 67.45 Kb.


Key words:

genome, human, DNA, RNA.

ABSTRACT

The concern of the researchers of the human genome has been clarify how, when and why the expression of genes is regulated. Classical Genetics says that genetic information is expressed in a linear fashion: deoxyribonucleic› ribonucleic acid › protein; however, the primacy of deoxyribonucleic acid has given way to the primacy of the environment, which provides the following flow of genetic information: environment › regulatory protein › deoxyribonucleic acid › ribonucleic acid › protein. One of the factors on the expression of inheritance is mediated by the environment proves Epigenetics, with an inheritance patterns of gene expression that are stable and occur without a change in the sequence of deoxyribonucleic acid. Understanding of these factors could revolutionize the approach of evolutionary Biology and the development and its application to medical science will determine definitely a new approach to the concepts of health and disease and will lay the way for new therapeutics.


REFERENCES

  1. Heredia D. El mito del gen: genética, epigenética y el bucle organismo

  2. ambiente. Medic Natur [Internet]. 2012 [citado 9 Sept 2014];6(1):42-9. Disponible en: http://dialnet.unirioja.es/servlet/articulo?codigo=3829210

  3. Cruz JA. Epigenética: un acercamiento al concepto. Ensayo Coloquio Nacional causalidad sobre Genética y Epigenética [Internet]. Surutato, Badiraguato, México: CEJUS- CIDE; 2012 Feb [citado 9 Sept 2014]. Disponible en: https://docs.google.com/viewer?a=v&pid=sites&srcid=ZGVm YXVsdGRvbWFpbnxjb2xvcXVpb25hY2lvbmFsY2lkZXxneDo1M2RlZmUwODQ4YTMyZDAx

  4. Jouve de la Barreda N. Biomarcadores epigeneticos. Monografía XXX [Internet]. Madrid: Departamento de Biología Celular y Genética. Universidad de Alcalá; 2010 [citado 9 Sept 2014]. Disponible en:

  5. http://www.analesranf.com/index.php/mono/article/viewFile/1065/1062

  6. González J, Cristiano E, Argibay P. Epigenética y epigenoma: un paso más allá en la etiología y potencial tratamiento de las enfermedades neurológicas. Medicina (B. Aires). 2011;71(4):390-6.

  7. García Robles R, Ayala Ramírez PA, Perdomo Velásquez SP. Epigenética: definición, bases moleculares e implicaciones en la salud y en la evolución humana. Rev Cienc Salud [Internet]. 2012 [citado 9 Sept 2014];10(1):59-71. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S1692- 72732012000100006

  8. Almon R. Epigenética y medicina. Rev Salud Pública Nutr. 2009 oct-dic;10(4):56-68.

  9. Valladares-Salgado A, Suárez-Sánchez F, Burguete-García AI, Cruz M. Epigenética de la obesidad infantil y de la diabetes. Rev Med Inst Mex Seguro Soc [Internet]. 2014 [citado 9 Sep 2014];52(Supl 1):S88-S93. Disponible en: www.medigraphic.com/pdfs/imss/im-2014/ims141o.pdf

  10. Richards CL, Bossdorf O, Pigliucci M. What role does heritable epigenetic variation play in phenotypic evolution? BioScience. 2010;60(3):232-7.




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Acta Med Cent. 2015;9