Pernas GA

Language: Spanish
References: 8
Page: 289-293
PDF size: 56.70 Kb.

ABSTRACT

Introduction: vitiligo is a benign skin disease characterized by depigmented patches of distinct borders. It is thought to be caused by an autoimmune reaction against melanocytes.
Objective: evaluate the prognostic factors for vitiligo associated with the evolution of patients with moderate or severe vitiligo treated with Melagenina Plus for a year.
Method: a retrospective study was conducted of a consecutive series of 62 patients with vitiligo with an affected skin area above 20% who presented at the Placental Histotherapy Center from August 2008 to August 2010. The variable response consisted in the response to the treatment at 2 years of follow-up. A logistic regression analysis was performed to determine the prognostic factors.
Results: the predominant age group was 40-49 years (28.6%). Most patients were female (61.4%). The most common race was white. The most frequent body surface range was 20-39%, with a mean value of 37.6%. Average evolution time was 8.4 years.
Conclusions: evolution time and body surface area were the only statistically significant variables found when the logistic regression model was applied. Both had a p value below 0.05.

REFERENCES

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