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2015, Number 1

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Rev Mex Pediatr 2015; 82 (1)

Salbutamol inhaled in newborn infant with transient tachypnea

Monzoy-Ventre MA, Rosas-Sumano AB, Hernández-Enríquez NP, Galicia-Flores L

Language: Spanish
References: 29
Page: 5-9
PDF size: 272.33 Kb.


ABSTRACT

Introduction: Transient tachypnea of the newborn is a selflimited disorder. The objective of this study was to know the usefulness of inhaled salbutamol in the clinical evolution of transient tachypnea of the newborn. Material and methods: Experimental clinical study in which salbutamol nebulizations were administered at doses of 0.10 mg/kg and 0.15 mg/kg. The study included newborns of 34 to 42 weeks gestation, hospitalized in special care newborn units of the Hospital Aurelio Valdivieso. After nebulizations, we assessed the respiratory frequency, Silverman-Anderson score, oxygen saturation, partial pressures of oxygen and carbon dioxide at 30 minutes, and at 1 and 4 hours. Results: Of the 46 newborns studied, 15 corresponded to the control group, 16 to the inhaled salbutamol at the 0.10 mg/kg dose and 15 to the 0.15 mg/kg dose. Comparison of the groups receiving salbutamol with the control group revealed an improvement in respiratory (p ≤ 0.05, with an OR: 2.29 and CI 95%: 1.191-4.417). Conclusions: Inhaled salbutamol could modify the clinical evolution of the transient tachypnea of the newborn by improving respiratory frequency.


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