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2015, Number 614

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Rev Med Cos Cen 2015; 72 (614)

Paragangliomas

Callaú BA
Full text How to cite this article

Language: Spanish
References: 11
Page: 91-93
PDF size: 305.94 Kb.


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ABSTRACT

Paragangliomas are rare tumors arising from chromaffin cells found outside the adrenal medulla. They are commonly confused with pheochromocytomas due to its clinical similarity, in this matter is important to distinguish between these two types of tumors, because of the implications that each one has. For example paragangliomas have a greater propensity to metastasize than the pheochromocytomas and are also more frequently associated with familial syndromes.


REFERENCES

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  2. Baysal BE, Ferrell RE, Willett- Brozick J, et al. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science 2000;287:848-851.

  3. Erickson D, KudvaYC, Ebersold MJ, et al. Benign paragangliomas: clinical presentation and treatmentoutcomes in 236 patients. J Clin Endocrinol Metab 2001;86:5210-5216.

  4. Gardner, D & Shoback, D. (2012) Médula suprarenal y paraganglios. En D. Cooper, Endocrinología Básica y Clínica de Greenspan (9° Ed pp 358-367). Mexico DF.

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  6. McWhinney SR, Pilarski RT, Forrester SR, et al. Large germline deletions of mitochondrial complex II subunits SDHB and SDHD in hereditary paraganglioma. J Clin Endocrinol MEtab 2004;89:5694- 5699.

  7. Melmed S, Polonsky K, Larsen P. & Kronenberg H. (2011). Endocrine hypertension. En G. Brent & T. Davies, Williams Textbook of Endocrinology (12° Ed pp 547-560) Philadelphia.

  8. Neumann HP, Bausch B, McWhinney SR, et al. Germ-line mutations innonsyndromic pheochrocytoma. N Engl J Med 2002; 346:1459-1466.

  9. Neumann HP, Pawlu C, Peczkowska M, et al. Distinct clinical features of paraganglioma sindromes associated with SDHB and SDHD gene mutations. JAMA 2004;292:943- 951.

  10. Young WF. Pheochromocytoma. Trends Endocrinol Metab 1993;4:122-127.

  11. Young WF, Maddox DE. Spells: in search of a cause. Mayo Clin Proc 1995;70:757-765




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Rev Med Cos Cen. 2015;72