medigraphic.com
Órgano oficial de la Sociedad Mexicana de Cirugía Dermatológica y Oncológica, AC

2003, Number 2

<< Back Next >>

Dermatología Cosmética, Médica y Quirúrgica 2003; 1 (2)

Itraconazole pulse-therapy in tinea capitis due to Microsporum canis. Report of 10 pediatric cases

Villanueva QG, Mayorga RJ, Barba GJF

Language: Spanish
References: 12
Page: 97-100
PDF size: 386.72 Kb.


ABSTRACT

We report 10 pediatric cases of Tinea Capitis caused by Microsporum Canis, at the Dermatological Institute of Jalisco Dr. José Barba Rubio. The main goal was to determinate the efficacy and safety with itraconazole pulse-therapy. The patients received three pulses of 5 mg/kg/day for a week every other week. Mycological and clinical cure was observed in all the cases. No side effects were observed.


REFERENCES

  1. Mayorga J, Espinoza-Gómez R, Villarreal-Parra I. Tiña de la cabeza. Observaciones clinicomicológicas en 30 pacientes. Dermatología Rev Mex 1999; 43 (6): 264-267

  2. Arenas R, Bonifaz A, Chávez G y cols. Primer consenso de micosis superficiales. Dermatología Rev Mex 1999; 43 (2): 80-88

  3. Van Cauteren H, Haykants J, De Coster R et al. Itraconazole pharmacologic studies in animals and humans. Rev Infect Dis 1987; 9 (supl): S43-46

  4. Cauwenbergh G, Degreef H, Haykants J et al. Pharmacokinetic profile of orally administered itraconazole in human skin. J Am Acad Dermatol 1998; 18 (2): 263-268

  5. Benett J. Fármacos antimicrobianos. Las bases farmacológicas de la terapéutica. Goodman & Gilman. 9a ed. México, 1996, II: 1254-1255

  6. Gupta AK, Hofstader SLR, Adam P et al. Tinea capitis: An overview with emphasis on management. Pediatr Dermatol 1999; 16 (3): 171-189

  7. Gupta AK, Sibbald G, Lynde CW et al. Onychomycosis in children: prevalence and treatment strategies. J Am Acad Dermatol 1997; 36 (3): 395-402

  8. Gupta AK, Alexis ME, Raboobee N et al. Itraconazole pulse therapy is effective in the treatment of tinea capitis in children: an open multicentre study. Br J Dermatol 1997; 137: 251-254

  9. Legendre R, Esola-Macre J. Itraconazole in the treatment of tinea capitis. J Am Acad Dermatol 1990; 23 (supl): 559-560

  10. Elewski BE. Tinea capitis: Itraconazole in Trichophyton tonsurans infection. J Am Acad Dermatol 1994; 31: 65-67

  11. Koumantaki E, Georgala S, Rallis E et al. Microsporum canis tinea capitis in a 8 month-old infant succesfully treated with 2 weekly pulses of oral itraconazole. Pediatr Dermatol 2001; 18 (1): 60-62

  12. López-Gómez S, Del Palacio A, Cutsem JV et al. Itraconazole versus griseofulvin in the treatment of tinea capitis: a double-blind randomized study in children. Int J Dermatol 1994; 33 (10): 743-747




2020     |     www.medigraphic.com