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2013, Number 5

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Ann Hepatol 2013; 12 (5)

Liver stiffness measurements increase after meal ingestion – an important step towards standardization

Tsochatzis EA, Burroughs AK

Language: English
References: 9
Page: 839-840
PDF size: 61.20 Kb.


Text Extraction

Comment
Transient elastogaphy (Fibroscan) is increasingly used in clinical practice for the non-invasive assessment of liver fibrosis, particularly in patients with chronic hepatitis C (CHC). When the technique was first described 10 years ago, the manufacturing company recommended criteria for reliable results, which included 10 valid measurements with a success rate of at least 60% and an interquartile range between median measurement values of less than 30%. Surprisingly, these criteria were met in only 21/40 transient elastography studies included in a metaanalysis.


REFERENCES

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  4. Arena U, Platon ML, Stasi C, Moscarella S, Assarat A, Bedogni G, Piazzolla V, et al. Liver stiffness is influenced by a standardized meal in patients with chronic hepatitis C virus at different stages of fibrotic evolution. Hepatology 2013; 58: 65-72.

  5. Berzigotti A, De Gottardi A, Vukotic R, Siramolpiwat S, Abraldes JG, García-Pagan JC, Bosch J. Effect of meal ingestion on liver stiffness in patients with cirrhosis and portal hypertension. PloS one 2013; 8: e58742.

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