Palacios CA, Pérez PM, Aguirre SJS, Franco GJ

Language: Spanish
References: 9
Page: 86-90
PDF size: 190.78 Kb.

ABSTRACT

Objectives: To report the incidence of cerebral salt wasting and syndrome of inappropriate secretion of antidiuretic hormone in cerebral injury patients admitted in the Intensive Care Department «Dr. Mario Shapiro». Design: A retrolective, observational study. Material and methods: We assessed all neurocritical patients over 18 years old with admission diagnosis of brain disease (subarachnoid hemorrhage, ischemic stroke, hemorrhagic stroke, brain tumors and Brain infection) to the Intensive Care Department «Dr. Mario Shapiro» from January 2011 to January 2013, having developed hyponatremia during their stay and complied with clinical and laboratory criteria to be classified as cerebral salt wasting and syndrome of inappropriate secretion of antidiuretic hormone. Results: In this retrospective, observational study, included 24 neurocritical patients who developed hyponatremia during their stay in the Intensive Care Unit, 14 females (58.3%) and 10 males (41.6%). The average age was 65 years and the admission diagnosis that prevailed was subarachnoid hemorrhage and hemorrhagic stroke. Time median of hyponatremia development was six days after admission and 6 patients (25%) were classified as cerebral salt wasting and 4 patients (16.6%) as syndrome of inappropriate secretion of antidiuretic hormone. Conclusions: Both syndromes may occur during neurocritcal patients’ clinical course. Differential diagnosis is essential because even if syndromes share clinical features, treatments are different for these two conditions and an inappropriate treatment may alter the clinical course of patients.

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