2015, Number 2
An Med Asoc Med Hosp ABC 2015; 60 (2)
Torres AO, Olvera GC, Terrés TF, Aguirre SJ, Franco GJ
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ABSTRACTToxic shock syndrome is a critical condition that develops from an immunological response from the host, targeted to a limited group of microbiological agents. The pathogenesis of the disease is complex, and involves antigenic factors from the pathogen that react with a series of inflammatory molecules released by the host. The management and treatment of toxic shock syndrome must be based on strong clinical evidence, it may represent a true challenge, and requires an early diagnosis. We present the case of a patient admitted to de Intensive Care Unit, who develops toxic shock syndrome from a soft tissue infection localized in the perineal region. The treatment involved measures to control a case of multiple organic failure in a setting of septic shock. Ultimately, the patient presented loss of distal-limb-structures besides an intense and adequate treatment, which was essential to stop progression to a fatal state. The objective of this review is to emphasize the importance of early diagnosis and treatment as there is not a frequent disease in our medium.