Uriegas-de-las-Fuentes Á, Manrique MA, Pérez-Valle E, Cerna-Cardona J, Gómez-Peña-Alfaro NS, Hernández-Velázquez NN, Espino-Cortés H, Peñavera-Hernández R, Chávez-García MÁ

Language: Spanish
References: 15
Page: 77-82
PDF size: 142.06 Kb.

ABSTRACT

Introduction. Eosinophilic esophagitis (EE) is an emerging disease characterized by a dense eosinophilic infiltration of the esophagus. The main symptoms are dysphagia and esophageal food obstruction, in response to a hypersensitivity reaction to different foods or aeroallergens. Material and methods. We developed an observational, cross-sectional, descriptive study. We included patients of both genders, children and adults, with clinical suspicion of EE or dysphagia. Also patients with esophageal food impaction with normal endoscopy and patients with gastroesophageal reflux disease (GERD) refractory to medical treatment were included. Patients with esophagitis and its complications and those with any endoscopic anomaly were excluded. Patients chosen for the study, four biopsies samples from the proximal and distal esophagus were obtain for histopathological analysis. In each patient we documented age, gender, reference service, medical history (allergies, asthma, rhinitis, atopic dermatitis and chronic cough), endoscopic and histopathological findings. Results. A total of 65 patients, 63 adults and 2 children were included, 39 men (60%) and 26 women(40%). The mean adult age was 50 years old. The indications for performing the EGD were: GERD (60%), dysphagia (35%), esophageal food impaction (5%). Eight patients (12%) had atopic diseases. Thirty-five patients (53.8%) had suggestive endoscopic findings of EE; 23(65.7%) had “trachealization” of the esophagus, 8 (22.8%) had crepe-paper mucosa and 4 (11.4%) had white patches. Forty-six patients had histopathological findings suggestive of GERD (70.7%), the rest were reported with normal mucosa. Not a single patient had an histopathological finding suggestive of EE. Conclusions. Despite the endoscopic findings and the high clinical suspicion, none of our patients had eosinophilic esophagitis.

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