medigraphic.com
SPANISH

MediSur

ISSN 1727-897X (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2015, Number 3

<< Back Next >>

Medisur 2015; 13 (3)

Kleine-Levin syndrome. A case report

Machado RA, Díaz LIR, de la Torre SME
Full text How to cite this article

Language: Spanish
References: 10
Page: 448-451
PDF size: 114.74 Kb.


Key words:

Kleine-Levin syndrome, case reports.

ABSTRACT

Kleine-Levin syndrome is a rare disorder characterized by recurrent episodes of hypersomnia, appetite disturbance, cognitive dysfunction and uninhibited behavior. It is estimated to affect one to five per million people and is four times more common in males. We present the case of an 18-year-old patient treated at the sleep disorders consultation in Villa Clara due to five episodes of hypersomnia lasting seven to ten days, separated by three or four months. During these periods he was irritable, apathetic and anorexic. When not suffering from hypersomnia, his behavior is normal. The patient meets the criteria of the 3rd International Classification of Sleep Disorders for the diagnosis of the Kleine-Levin syndrome. This case is presented given the rarity of this condition; the diagnosis was made 15 months after its onset and there are no previous references in Cuba.


REFERENCES

  1. Billiard M. Recurrent Hypersomnia. In: Montagna P, Chokroverty S, editors. Handbook of Clinical Neurology. Amsterdam: Elsevier; 2011. p. 815-23.

  2. Arnulf I, Zeitzer JM, File J, Farber N, Mignot E. Kleine–Levin syndrome: a systematic review of 186 cases in the literature. Brain. 2005 ; 128(Pt 2): 2763-76.

  3. Arias M, Crespo-Iglesias JM, Pérez J, Requena-Caballero I, Sesar A, Peleteiro Fernández M. Síndrome de Kleine-Levin aportación diagnóstica de la SPECT cerebral. REV NEUROL. 2002 ; 35 (6): 531-3.

  4. Billiard M, Jaussent I, Dauvalliers Y, Besset A. Recurrent hypersomnia: A review of 339 cases. Sleep Medicine Reviews. 2011 ; 15: 247-57.

  5. Aguilera L, Díaz M, Mena B, Erazo S, Núñez JC. Síndrome de Kleine-Levin. Caso clínico y revisión del tema. Rev Hosp Clín Chile. 2009 ; 20: 15-9.

  6. Pedrós A, Hoyo B, López E. Síndrome de Kleine-Levin: análisis clínico comparativo. A propósito de dos casos. Psiq Biol. 2011 ; 18 (3): 124-6.

  7. American Academy of Sleep Medicine. International classification of sleep disorders [Internet]. Darien IL: American Academy of Sleep Medicine; 2014. [ cited 23 Feb 2015 ] Available from: http://www.aasmnet.org/library/default.aspx?id= 9.

  8. Huang YS, Lakkis C, Guilleminault Ch. Kleine-Levin Syndrome: current status. Med Clin North Am. 2010 ; 94 (3): 557-62.

  9. Shukla G, Bhaia M, Singh S, Goyal V, Srivastava T, Behari M. Atypical Kleine–Levin syndrome: can insomnia and anorexia be features too?. Sleep Med. 2008 ; 9 (2): 172-6.

  10. Miglis M, Guilleminault Ch. Kleine-Levin syndrome: a review. Nat Sci Sleep. 2014 ; 6: 19-26.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Medisur. 2015;13