2012, Number 3
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Ann Hepatol 2012; 11 (3)
Causes of death after liver transplantation
Nensi A, Chandok N
Language: English
References: 7
Page: 415-417
PDF size: 68.07 Kb.
Text Extraction
Dear Editor,
As in many areas in medicine, database mining is
in vogue in transplant hepatology. Large datasets,
such as that of the United Network for Organ Sharing
(UNOS), have indeed generated many high impact
outcome studies that have advanced the
specialty on several fronts, particularly concerning
our understanding of recipient mortality. Mortality
of the recipient is indeed the single most important
clinical outcome when assessing the safety, efficacy,
and cost-effectiveness of liver transplant surgery.
UNOS and similar databases provide a wealth of
knowledge on overall recipient mortality, and enable
multivariable analyses of clinico-demographic variables
in both donors and recipients to identify
risk- or protective factors for recipient mortality.
REFERENCES
Aberg F, Isoniemi H, Hockerstedt K. Long-term results of liver transplantation. Scand J Surg 2011; 100: 14-21.
Johnston SD, Morris JK, Cramb R, Gunson BK, Neuberger J. Cardiovascular morbidity and mortality after orthotopic liver transplantation. Transplantation 2002; 73: 901-6.
Gonwa TA, Mai ML, Melton LB, Hays SR, Goldstein RM, Levy MF, et al. End-stage renal disease (ESRD) after orthotopic liver transplantation (OLTX) using calcineurin-based immunotherapy: risk of development and treatment. Transplantation 2001; 72: 1934-9.
Pruthi J, Medkiff KA, Esrason KT, Donovan JA, Yoshida EM, Erb SR, et al. Analysis of causes of death in liver transplant recipients who survived more than 3 years. Liver Transpl 2001; 7: 811-5.
Kotlyar DS, Campbell MS, Reddy KR. Recurrence of diseases following orthotopic liver transplantation. Am J Gastroenterol 2006; 101: 1370-8.
Watt KD, Pedersen RA, Kremers WK, Heimbach JK, Sanchez W, Gores GJ. Long-term probability of and mortality from de novo malignancy after liver transplantation. Gastroenterology 2009; 137: 2010-7.
Moon JI, Barbeito R, Faradji RN, Gaynor JJ, Tzakis AG. Negative impact of new-onset diabetes mellitus on patient and graft survival after liver transplantation: Long-term follow up. Transplantation 2006; 82: 1625-8.
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