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2015, Number 2

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Dermatología Cosmética, Médica y Quirúrgica 2015; 13 (2)

Psoriasis as an Independent Risk for Developing Cardiovascular Disease in Patients Treated at imss umae 25, Monterrey, Nuevo León, Mexico

González SA, Amaya GM
Full text How to cite this article

Language: Spanish
References: 14
Page: 103-107
PDF size: 154.59 Kb.


Key words:

psoriasis, acute myocardial infarction, cerebrovascular insult.

ABSTRACT

Background: psoriasis is a chronic disease that affects approximately 2% of world’s population a relationship between this and cardiovascular risk has been established. However, the possibility of psoriasis as an independent cardiovascular risk factor has been propound.
Methodology and material: retrospective analytic studies of cases and controls. Patients older than 30 years who were diagnosed with psoriasis, between October 1st 2011 and September 30th 2012. Inferential statistics Student’s T test was used for quantitative variables and squared Chi for qualitative variables. Risk factors were analyzed through odds ratio in the bivariate analysis. With p<0.05 as significance.
Results: 120 patients were included, 40 cases and 80 controls. Patients were arranged by age and gender. For cases σ = 48 ± 18 while for controls σ = 46 ± 16, with a significance of p 0.522. Regarding the cardiovascular incidents (cases) 28 males and 12 females (ami) and controls (56 males, 24 females) or 1.0 and ci = 0.43–2.28.
Conclusions: psoriasis is not a direct risk factor to develop cardiovascular events.


REFERENCES

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  2. Anselmi, C.L., Galimberti, M.L., De Luca, D.A. et al., “Psoriasis: prevalencia de comorbilidades cardiovasculares en la población del Plan de Salud del Hospital Italiano de Buenos Aires. Estudio de corte, 2010”, Dermatol. Argent., 2012, 18 (3): 239-244.

  3. Ríos Yuil, J.M., Yuil de Ríos, E., “Psoriasis y enfermedad cardiovascular: mecanismos inmunológicos y moleculares”, Rev. Med. Cient., 2011, 24 (1): 33-41.

  4. Choi, W.J., Park, E.J., Kwon, I.H. et al., “Association between psoriasis and cardiovascular risk factors in Korean patients”, Ann Dermatol, 2010, 22 (3): 300-306.

  5. Cohen, A.D., Weitzman, D., Dreiher, J. et al., “Psoriasis and hypertension: a case-control study, Acta Derm. Venereol., 2010, 90: 23-26.

  6. Arican, O., Aral, M. et al., “Serum levels of tnf-alpha, ifn-y, il-6, il-8, il-12, il-17, and il-18 in Patients with active Psoriasis and Correlation with Disease Severity”, Mediators inflamm., 2005 (5): 273-279.

  7. Ghazizadeh, R., Shimizu, H., Tosa, M., Ghazizadeh, M., “Pathogenic mechanisms shared between psoriasis and cardiovascular disease”, Int J Med Sci, 2010, 7 (5): 284-289.

  8. Setty, A.R., Curhan, G., Choi, H.K., “Obesity, waist circumference, weight change and the risk of psoriasis in women: Nurses Health Study II”, Arch Intern Med., 2007, 167 (15): 1670-1675.

  9. Fernández, T.R., Pita, F.S., Fonseca, E., “Psoriasis and cardiovascular risk. Assessement by different cardiovascular risk scores”, J Eur Acad Dermatol Venereol, 2012, 27 (12), 1566-1570.

  10. Farías, M.M., Serrano, V., De la Cruz, C., “Psoriasis y obesidad: revisión y recomendaciones prácticas”, Actas Dermosifiliogr, 2011, 102: 505-509.

  11. Gisondi, P., Farina, S., Vittoria, M. et al., “Usefulness of the Framingham Risk Score in Patients with Chronic Psoriasis”, Am J Cardiol, 2010, 106: 1754-1757.

  12. González, M.A., González, C. et al., “Psoriasis: A skin Disease Associated With Increased Cardiovascular Risk”, Actas Dermosifiliogr, 2012, 103 (7): 595-598.

  13. Sidiropoulos, P., Karvounaris, S., Boumpas, D. et al., “Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology and clinical implications”, Arthritis Res Ther, 2008, 10: 207.

  14. Rizvia, A., “Inflammation markers as mediators of vasculo-endothelial dysfunction and atherosclerosis in the metabolic syndrome and type 2 diabetes”, Chin Med J, 2007, (120): 1918-1924.




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Dermatología Cosmética, Médica y Quirúrgica. 2015;13