Delgado-Quiñones EG, Jiménez-Mayagoitia TF, Hernández-Rivera LN

Language: Spanish
References: 28
Page: 314-317
PDF size: 590.38 Kb.

ABSTRACT

Calcific uremic arteriopathy, previously called calciphylaxis, is an entity characterized by the presence of ischemic necrosis areas with extensive calcifying in the dermoepidermal cystic medial arterioles. It has a presentation related to patients with kidney disease on dialysis or transplant patients with dysfunctional grafts. The unchaining mechanisms are little known. However, it is known that alterations proper of the uremic state and calcium-phosphor metabolism are important. We present a case of a patient who began with the condition a year before, with Systemic Arterial Alteration (SAA) background and chronic kidney disease (CKD) secondary to a 4-years evolution pre-eclampsia under treatment with peritoneal dialysis. It initially showed painful indurated lesion in the inner part of the right thigh, subsequently, presenting central dermal necrosis. It was performed a dermal punch confirming the diagnosis and complementary studies.

REFERENCES

1. Seyle H. Calciphylaxis. Chicago, IL. University of Chicago Press. 1962.

2. Coates T, Kirkland GS, Dymock RB, et al. Cutaneous necrosisfrom calcific uremic arteriolopathy. Am J Kidney Dis 1998; 32: 384-91.

3. Janigan DT, Hirsch DJ, Klassen GA, Mac Donald AS: Calcified subcutaneous arterioles with infarcst of the subcutis and skin (calciphylaxis) in chronic renal failure. Am J Kidney Dis 35:588-97, 2000.

4. Perez JE. Calcifilaxis y enfermedad renal crónica. Acta Med Colomb 2011; 36: 149-152.

5. Mazhar AR, Johnson RJ, Villen D. Risk factors and mortality associated with calciphylaxis in end-stage renal disease. Kidney Int. 2001;60: 324–32.

6. Esteve V, Almirall J, et al. Arteriopatía urémica calcificante (calcifilaxis): incidencia, formas de presentación y evolución. Nefrología 2007; 27 (5): 82-87.

7. Wilmer WA, Magro CM. Calciphylaxis: Emerging concepts in prevention, diagnosis, and treatment. Semin Dial. 2004;15: 172–86.

8. Ahmad S. Renal osteodystrophy -metastatic calcification. En: Ahmad S, editor. Manual of Clinical Dialysis. 2 ed. New York: Editorial Springer; 2009. 15: p. 211–26.

9. Llach F. The evolving clinical features of calciphylaxis. Kidney Int. 2003; 122–4.

10. Camba M, Bravo J, Blanco R, Borrajo M, Iglesias I. Calcifilaxis severa en paciente en diálisis, trasplantado hepático e hipocalcemia de larga evolución. Nefrología. 2008; 28:226–7.

11. Rodríguez Villareal I, Callejas R, Sánchez M, Laso N, Gallar N, Ortega O, et al. Dial Traspl 2010; 31 (3): 76-78.

12. Gómez de la Fuente E, F.J. Vicentea, José G. Álvarea, Elena Naza, Sara I. Palencia, F. Pinedob y José L. López-Estebaranz. Calcifilaxis en pacientes dializados. Actas Dermosifiliogr 2004;95(3):178-8213.

13. Zitt E, König M, Vychytil A, et al. Use of sodium thiosulphate in a multi-interventional setting for the treatment of calciphylaxis in dialysis patients. Nephrol Dial Transplant. Jan 4 2013.

14. Torregrosa JV, Durán CE, Barros X, Blasco M, Arias M, Cases A, et al. Successful treatment of calcific uraemic arteriolopathy with bisphosphonates. Nefrologia. 2012;32(3):329-34.

15. Seyle H. Calciphylaxis. Chicago, IL. University of Chicago Press. 1962.

16. Coates T, Kirkland GS, Dymock RB, et al. Cutaneous necrosisfrom calcific uremic arteriolopathy. Am J Kidney Dis 1998; 32: 384-91.

17. Janigan DT, Hirsch DJ, Klassen GA, Mac Donald AS: Calcified subcutaneous arterioles with infarcst of the subcutis and skin (calciphylaxis) in chronic renal failure. Am J Kidney Dis 35:588-97, 2000.

18. Perez JE. Calcifilaxis y enfermedad renal crónica. Acta Med Colomb 2011; 36: 149-152.

19. Mazhar AR, Johnson RJ, Villen D. Risk factors and mortality associated with calciphylaxis in end-stage renal disease. Kidney Int. 2001;60: 324–32.

20. Esteve V, Almirall J, et al. Arteriopatía urémica calcificante (calcifilaxis): incidencia, formas de presentación y evolución. Nefrología 2007; 27 (5): 82-87.

21. Wilmer WA, Magro CM. Calciphylaxis: Emerging concepts in prevention, diagnosis, and treatment. Semin Dial. 2004;15: 172–86.

22. Ahmad S. Renal osteodystrophy -metastatic calcification. En: Ahmad S, editor. Manual of Clinical Dialysis. 2 ed. New York: Editorial Springer; 2009. 15: p. 211–26.

23. Llach F. The evolving clinical features of calciphylaxis. Kidney Int. 2003; 122–4.

24. Camba M, Bravo J, Blanco R, Borrajo M, Iglesias I. Calcifilaxis severa en paciente en diálisis, trasplantado hepático e hipocalcemia de larga evolución. Nefrología. 2008; 28:226–7.

25. Rodríguez Villareal I, Callejas R, Sánchez M, Laso N, Gallar N, Ortega O, et al. Dial Traspl 2010; 31 (3): 76-78.

26. Gómez de la Fuente E, F.J. Vicentea, José G. Álvarea, Elena Naza, Sara I. Palencia, F. Pinedob y José L. López-Estebaranz. Calcifilaxis en pacientes dializados. Actas Dermosifiliogr 2004;95(3):178-8213.

27. Zitt E, König M, Vychytil A, et al. Use of sodium thiosulphate in a multi-interventional setting for the treatment of calciphylaxis in dialysis patients. Nephrol Dial Transplant. Jan 4 2013.

28. Torregrosa JV, Durán CE, Barros X, Blasco M, Arias M, Cases A, et al. Successful treatment of calcific uraemic arteriolopathy with bisphosphonates. Nefrologia. 2012;32(3):329-34.