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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2015, Number 09

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Ginecol Obstet Mex 2015; 83 (09)

Primary hyperparathyroidism in pregnancy: a case report and bibliographical review

Herrera-Ortiz A, Morales-Domínguez L
Full text How to cite this article

Language: Spanish
References: 10
Page: 556-560
PDF size: 289.17 Kb.


Key words:

Hyperparathyroidism, Hypercalcaemia, Pregnancy.

ABSTRACT

Primary hyperparathyroidism in pregnant women is an uncommon disease. It could be easily misdiagnosed because physiologic changes during pregnancy; in some cases, patients could remain asymptomatic maintaining elevated calcium serum levels, and this situation represents a threat to the health of both mother and fetus. Maternal complications of primary hyperparathyroidism include nepfhrolithiasis, pancreatitis, cardiac arrhythmias, hypertension, nausea and vomiting. Most commonly, the underlying aetiology is a solitary parathyroid adenoma whereby parathyroidectomy is the only cure. We present the case of a 21-year old patient, with primary hyperparathyroidism diagnosed in the third trimester of pregnancy, complicated with pancreatitis and gestational hypertension. We performed a caesarean section due to elevated calcium levels. Post-caesarean section, she was referred to a third level institute (National Institute of Cancerology of Mexico), were she undergone parathyroidectomy, with benign histopathological results. An appropriate medical/surgical management of hyperparathyroidism during pregnancy is necessary for avoiding maternal and fetal complications.


REFERENCES

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  2. Dochez Vincent, Ducarme Guillaume. Primary hyperparathyroidism during pregnancy. Arch Gynecol Obstet (2015) 291:259-263

  3. Nash E, Ranka P, Tarigopula G, Rashid T. Primary hyperparathyroidism in pregnancy leading to hypercalcaemic crisis and uraemic encephalopathy. BMJ Case Rep Mar 27;2015

  4. Hirsch Dania, Kopel Vered, Nadler Varda, Levy Sigal, Toledano Yoel, Tsvetov Gloria. Pregnancy outcomes in women with primary hyperparathyroidism. J Clin Endocrinol Metab, May 2015, 100(5): 2115-2122.

  5. Walker A, Fraile JJ, Hubbard JG. Parathyroidectomy in pregnancy— a single centre experience with review of evidence and proposal for treatment algorithim. Gland Surgery 2014;3(3):158-164

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  7. Abood Ali, Vestergaard. Pregnancy outcomes in women with primary hyperparathyroidism. European Journal of Endocrinology (2014) 171, 69-76

  8. Razavi Christopher R., Charitou Marina, Marzouk Mark, Maternal atypical parathyroid adenoma as a cause of newborn hypocalcemic tetany. Otolaryngol Head Neck Surg. December 2014. Vol. 151 no. 6 1084-1085

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  10. Banu Aktas Yilmaz, Altay Mustafa, Degertekin Ceyla Konca, Cimen Ali Riza, Iyidir Ozlem Turhan, Biri Aydan, Yuksel Osman, Torüner Füsun Balos, Arslan Metin. Hyperparathyroid crisis presenting with hyperemesis gravidarum. Arch Gynecol Obstet (2014) 290:811-814.




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Ginecol Obstet Mex. 2015;83