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2015, Number 2

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Rev Mex Traspl 2015; 4 (2)

Liver-kidney transplants. First successful cases reported in Mexico

Mendoza-Sánchez F, Gómez-Navarro B, González-Espinoza E, Navarro-López R, Aguayo-Villaseñor FJ, Santiago-Luna E, Fuentes-Orozco C, Ruíz-Félix OA, Nuño-Díaz D, Camacho-Álvarez BB, Acevedo-Luna D, Cortés-Lares JA, Mendoza-Medina DF

Language: Spanish
References: 27
Page: 80-83
PDF size: 198.84 Kb.


ABSTRACT

Introduction: Simultaneous liver-kidney transplantation (SLK) is an accepted procedure for patients with terminal liver disease and irreversible kidney disease, and has increased significantly since the introduction of the MELD Model for end-stage liver disease. SLK is a procedure performed routinely in many transplant centers. It represents 1-8% of patients requiring renal transplantation. Survival rates have been considered satisfactory in many transplant centers in US and Europe; with lower rates of morbidity and mortality. In Mexico there are no reports of these transplants, we present the first cases of success. Presentation of cases: Case 1. 57 year-old woman, liver-kidney transplant on 06-03-2005 by autoimmune liver cirrhosis and lupus nephritis undergoing hemodialysis, hepatic-functional Child-Pugh’s score «C» 10 points, MELD 24, adequate performance with normal hepatic and renal function to 10 years 3 months after transplantation. Case 2. 49 year-old woman, liver-kidney transplant on 16-07-2012 by severe polycystic liver and kidney disease and chronic renal failure grade IV, glomerular filtration rate: 26.8 mL/min of 13 years of evolution, hepatorenal Child-Pugh functional stage: 6 points and MELD 15, she has presented adequate performance with normal hepatic and renal function 2 years 11 months after transplantation. Conclusion: Combined liver-kidney transplantation is an appropriate procedure in patients with end-stage liver failure and irreversible renal dysfunction. We present the first two cases with good results in Mexico.


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