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2015, Number 2

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Rev Clin Esc Med 2015; 5 (2)

Cryptogenic organizing pneumonia

Sibaja CM, Monge BC
Full text How to cite this article

Language: English
References: 33
Page: 11-16
PDF size: 349.30 Kb.


Key words:

Cryptogenic organizing pneumonia, intraalveolar fibrosis, butterfly pattern, bronchiolitis obliterans organizing pneumonia, alveolar wall, Masson bodies.

ABSTRACT

Cryptogenic organizing pneumonia (COP) is a distinct histopathologic entity characterized by Masson bodies which are intraalveolar buds of granulation tissue; consisting of connective tissue and myofibroblasts. This pathologic pattern when present with the characteristic imaging and clinical features of COP defines the diagnosis of the disease. A specific etiology is not found. Treatment with corticosteroids results in a rapid clinical and imaging improvement but unfortunately relapses are common upon decreasing the dose or stopping the treatment. This case report describes a typical case of COP with the characteristic improvement with corticosteroid therapy and relapse upon treatment taper


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Rev Clin Esc Med. 2015;5